| Title |
PEG Hydrogels for the Controlled Release of Biomolecules in Regenerative Medicine
|
|---|---|
| Published in |
Pharmaceutical Research, December 2008
|
| DOI | 10.1007/s11095-008-9801-2 |
| Pubmed ID | |
| Authors |
Chien-Chi Lin, Kristi S. Anseth |
| Abstract |
Polyethylene glycol (PEG) hydrogels are widely used in a variety of biomedical applications, including matrices for controlled release of biomolecules and scaffolds for regenerative medicine. The design, fabrication, and characterization of PEG hydrogels rely on the understanding of fundamental gelation kinetics as well as the purpose of the application. This review article will focus on different polymerization mechanisms of PEG-based hydrogels and the importance of these biocompatible hydrogels in regenerative medicine applications. Furthermore, the design criteria that are important in maintaining the availability and stability of the biomolecules as well as the mechanisms for loading of biomolecules within PEG hydrogels will also be discussed. Finally, we overview and provide a perspective on some of the emerging novel design and applications of PEG hydrogel systems, including the spatiotemporal-controlled delivery of biomolecules, hybrid hydrogels, and PEG hydrogels designed for controlled stem cell differentiation. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,253 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 17 | 1% |
| Germany | 3 | <1% |
| United Kingdom | 3 | <1% |
| Brazil | 2 | <1% |
| India | 2 | <1% |
| Spain | 2 | <1% |
| Switzerland | 2 | <1% |
| Canada | 2 | <1% |
| Austria | 1 | <1% |
| Other | 7 | <1% |
| Unknown | 1212 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 327 | 26% |
| Student > Master | 186 | 15% |
| Student > Bachelor | 158 | 13% |
| Researcher | 121 | 10% |
| Student > Doctoral Student | 74 | 6% |
| Other | 140 | 11% |
| Unknown | 247 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 255 | 20% |
| Chemistry | 191 | 15% |
| Materials Science | 114 | 9% |
| Agricultural and Biological Sciences | 104 | 8% |
| Biochemistry, Genetics and Molecular Biology | 88 | 7% |
| Other | 211 | 17% |
| Unknown | 290 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2024.
All research outputs
#1,791,367
of 23,986,470 outputs
Outputs from Pharmaceutical Research
#63
of 2,921 outputs
Outputs of similar age
#7,498
of 173,285 outputs
Outputs of similar age from Pharmaceutical Research
#2
of 36 outputs
Altmetric has tracked 23,986,470 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,921 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,285 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.