| Title |
Gamma-Linolenic Acid Levels Correlate with Clinical Efficacy of Evening Primrose Oil in Patients with Atopic Dermatitis
|
|---|---|
| Published in |
Advances in Therapy, January 2014
|
| DOI | 10.1007/s12325-014-0093-0 |
| Pubmed ID | |
| Authors |
Dagmar Simon, Peter A. Eng, Siegfried Borelli, Roland Kägi, Christian Zimmermann, Catherine Zahner, Jürgen Drewe, Lorenzo Hess, Giovanni Ferrari, Stephan Lautenschlager, Brunello Wüthrich, Peter Schmid-Grendelmeier |
| Abstract |
Atopic dermatitis (AD) has been related to a deficiency of delta-6-desaturase, an enzyme responsible for the conversion of linoleic acid to gamma-linolenic acid (GLA). Evening primrose oil (EPO) contains high amounts of GLA. Therefore, this study investigated whether EPO supplementation results in an increase in plasma GLA and its metabolite dihomo-gamma-linolenic acid (DGLA) correlating with clinical improvement of AD, assessed by the SCORing Atopic Dermatitis (SCORAD) index. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| Unknown | 99 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 16% |
| Student > Bachelor | 16 | 16% |
| Student > Master | 11 | 11% |
| Student > Ph. D. Student | 7 | 7% |
| Student > Doctoral Student | 6 | 6% |
| Other | 14 | 14% |
| Unknown | 30 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 21% |
| Agricultural and Biological Sciences | 14 | 14% |
| Nursing and Health Professions | 6 | 6% |
| Biochemistry, Genetics and Molecular Biology | 5 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
| Other | 12 | 12% |
| Unknown | 38 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2023.
All research outputs
#2,230,218
of 24,972,914 outputs
Outputs from Advances in Therapy
#209
of 2,589 outputs
Outputs of similar age
#25,592
of 317,564 outputs
Outputs of similar age from Advances in Therapy
#1
of 18 outputs
Altmetric has tracked 24,972,914 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,589 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,564 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.