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Annexins of schistosomes

Overview of attention for article published in British Journal of Pharmacology, December 2014
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Title
Annexins of schistosomes
Published in
British Journal of Pharmacology, December 2014
DOI 10.1111/bph.12898
Pubmed ID
Authors

Chiuan Yee Leow, Charlene Willis, Andreas Hofmann, Malcolm K Jones

Abstract

Neglected tropical diseases are a group of some 17 diseases that afflict poor and predominantly rural people in developing nations. One significant disease that contributes to substantial morbidity in endemic areas is schistosomiasis, caused by infection with one of 5 species of blood fluke belonging to the trematode genus Schistosoma. Although there is one drug available for treatment of affected individuals in clinics, or for mass administration in endemic regions, there is a need for new therapies. A prominent target organ of schistosomes, either for drug or vaccine development, is the peculiar epithelial syncytium that forms the body wall (tegument) of this parasite. This dynamic layer is maintained and organized by concerted activity of a range of proteins, among which are the abundant tegumentary annexins. In this review, we will outline advances in structure-function analyses of these annexins, as a means to understanding tegument cell biology in host- parasite interaction and their potential exploitation as targets for anti-schistosomiasis therapies.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 17%
Professor 5 11%
Student > Doctoral Student 4 9%
Student > Bachelor 4 9%
Student > Ph. D. Student 4 9%
Other 10 21%
Unknown 12 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 19%
Agricultural and Biological Sciences 7 15%
Medicine and Dentistry 7 15%
Veterinary Science and Veterinary Medicine 3 6%
Immunology and Microbiology 3 6%
Other 5 11%
Unknown 13 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2015.
All research outputs
#19,177,100
of 24,417,958 outputs
Outputs from British Journal of Pharmacology
#6,526
of 7,563 outputs
Outputs of similar age
#251,859
of 362,067 outputs
Outputs of similar age from British Journal of Pharmacology
#79
of 101 outputs
Altmetric has tracked 24,417,958 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,563 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,067 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.