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Tracing innate immune defences along the path of Listeria monocytogenes infection

Overview of attention for article published in Immunology & Cell Biology, April 2014
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Title
Tracing innate immune defences along the path of Listeria monocytogenes infection
Published in
Immunology & Cell Biology, April 2014
DOI 10.1038/icb.2014.27
Pubmed ID
Authors

Tim Regan, John MacSharry, Elizabeth Brint

Abstract

The pathogenic gram-positive bacteria, Listeria monocytogenes is a facultative infectious intracellular pathogen that causes listeriosis. Effective elimination of infection is dependent upon a functioning innate immune system and activation of inflammatory responses by pathogen recognition receptors (PRRs). In this review, we trace the route of L. monocytogenes invasion as it disseminates from the intestinal epithelium, through the bloodstream of the host, to the liver and spleen. Along this route, we highlight the diverse, region specific, innate defences in place throughout the course of infection. We provide an overview of recent advances in our knowledge of key innate immune defences against L. monocytogenes, focusing on the PRRs in various cell types known to be critical in the detection of this pathogen.

X Demographics

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Portugal 1 2%
Ireland 1 2%
Germany 1 2%
Unknown 46 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 26%
Student > Ph. D. Student 9 18%
Student > Master 5 10%
Professor 4 8%
Student > Bachelor 4 8%
Other 12 24%
Unknown 3 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 38%
Immunology and Microbiology 17 34%
Biochemistry, Genetics and Molecular Biology 5 10%
Veterinary Science and Veterinary Medicine 1 2%
Psychology 1 2%
Other 3 6%
Unknown 4 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2015.
All research outputs
#16,722,190
of 25,374,917 outputs
Outputs from Immunology & Cell Biology
#1,563
of 1,848 outputs
Outputs of similar age
#138,360
of 239,871 outputs
Outputs of similar age from Immunology & Cell Biology
#10
of 19 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,848 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 239,871 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.