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An Update on Plant Derived Anti-Androgens

Overview of attention for article published in International Journal of Endocrinology and Metabolism, December 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#5 of 130)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
9 news outlets
blogs
2 blogs
twitter
30 X users
facebook
4 Facebook pages
wikipedia
3 Wikipedia pages
video
8 YouTube creators

Citations

dimensions_citation
43 Dimensions

Readers on

mendeley
288 Mendeley
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Title
An Update on Plant Derived Anti-Androgens
Published in
International Journal of Endocrinology and Metabolism, December 2012
DOI 10.5812/ijem.3644
Pubmed ID
Authors

Paul Grant, Shamin Ramasamy

Abstract

Anti-androgens are an assorted group of drugs and compounds that reduce the levels or activity of androgen hormones within the human body. Disease states in which this is relevant include polycystic ovarian syndrome, hirsutism, acne, benign prostatic hyperplasia, and endocrine related cancers such as carcinoma of the prostate. We provide an overview and discussion of the use of anti-androgen medications in clinical practice and explore the increasing recognition of the benefits of plant-derived anti-androgens, for example, spearmint tea in the management of PCOS, for which some evidence about efficacy is beginning to emerge. Other agents covered include red reishi, which has been shown to reduce levels 5-alpha reductase, the enzyme that facilitates conversion of testosterone to dihydrotestosterone (DHT); licorice, which has phytoestrogen effects and reduces testosterone levels; Chinese peony, which promotes the aromatization of testosterone into estrogen; green tea, which contains epigallocatechins and also inhibits 5-alpha reductase, thereby reducing the conversion of normal testosterone into the more potent DHT; black cohosh, which has been shown to kill both androgenresponsive and non-responsive human prostate cancer cells; chaste tree, which has a reduces prolactin from the anterior pituitary; and saw palmetto extract, which is used as an anti-androgen although it shown no difference in comparison to placebo in clinical trials.

X Demographics

X Demographics

The data shown below were collected from the profiles of 30 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 288 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 3 1%
United States 2 <1%
Switzerland 1 <1%
Canada 1 <1%
Portugal 1 <1%
Unknown 280 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 104 36%
Student > Master 35 12%
Researcher 23 8%
Other 18 6%
Student > Postgraduate 18 6%
Other 41 14%
Unknown 49 17%
Readers by discipline Count As %
Medicine and Dentistry 105 36%
Nursing and Health Professions 40 14%
Agricultural and Biological Sciences 33 11%
Biochemistry, Genetics and Molecular Biology 16 6%
Pharmacology, Toxicology and Pharmaceutical Science 13 5%
Other 34 12%
Unknown 47 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 113. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2024.
All research outputs
#373,528
of 25,523,622 outputs
Outputs from International Journal of Endocrinology and Metabolism
#5
of 130 outputs
Outputs of similar age
#2,413
of 286,403 outputs
Outputs of similar age from International Journal of Endocrinology and Metabolism
#1
of 9 outputs
Altmetric has tracked 25,523,622 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 130 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.4. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,403 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them