| Title |
Curcumin and Dimethoxycurcumin Induced Epigenetic Changes in Leukemia Cells
|
|---|---|
| Published in |
Pharmaceutical Research, September 2014
|
| DOI | 10.1007/s11095-014-1502-4 |
| Pubmed ID | |
| Authors |
Hazem E. Hassan, Samuel Carlson, Inas Abdallah, Thomm Buttolph, Karen C. Glass, Tamer E. Fandy |
| Abstract |
Curcumin is an ideal chemopreventive and antitumor agent characterized by poor bioavailability and low stability. The development of synthetic structural analogues like dimethoxycurcumin (DMC) could overcome these drawbacks. In this study we compared the cytotoxicity, metabolism and the epigenetic changes induced by both drugs in leukemia cells. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| France | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 1 | 3% |
| Unknown | 29 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 27% |
| Researcher | 5 | 17% |
| Student > Doctoral Student | 2 | 7% |
| Other | 2 | 7% |
| Student > Master | 2 | 7% |
| Other | 4 | 13% |
| Unknown | 7 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 20% |
| Medicine and Dentistry | 5 | 17% |
| Biochemistry, Genetics and Molecular Biology | 4 | 13% |
| Agricultural and Biological Sciences | 2 | 7% |
| Neuroscience | 2 | 7% |
| Other | 2 | 7% |
| Unknown | 9 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2017.
All research outputs
#17,726,563
of 22,763,032 outputs
Outputs from Pharmaceutical Research
#2,432
of 2,855 outputs
Outputs of similar age
#159,972
of 237,921 outputs
Outputs of similar age from Pharmaceutical Research
#23
of 35 outputs
Altmetric has tracked 22,763,032 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,855 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 237,921 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.