| Title |
Alcohol intake as a risk factor for fracture
|
|---|---|
| Published in |
Osteoporosis International, September 2004
|
| DOI | 10.1007/s00198-004-1734-y |
| Pubmed ID | |
| Authors |
John A. Kanis, Helena Johansson, Olof Johnell, Anders Oden, Chris De Laet, John A. Eisman, Huibert Pols, Alan Tenenhouse |
| Abstract |
High intakes of alcohol have adverse effects on skeletal health, but evidence for the effects of moderate consumption are less secure. The aim of this study was to quantify this risk on an international basis and explore the relationship of this risk with age, sex, and bone mineral density (BMD). We studied 5,939 men and 11,032 women from three prospectively studied cohorts comprising CaMos, DOES, and the Rotterdam Study. Cohorts were followed for a total of 75,433 person-years. The effect of reported alcohol intake on the risk of any fracture, any osteoporotic fracture, and hip fracture alone was examined using a Poisson model for each sex from each cohort. Covariates examined included age and BMD. The results of the different studies were merged using weighted beta-coefficients. Alcohol intake was associated with a significant increase in osteoporotic and hip fracture risk, but the effect was nonlinear. No significant increase in risk was observed at intakes of 2 units or less daily. Above this threshold, alcohol intake was associated with an increased risk of any fracture (risk ratio [RR] = 1.23; 95% CI, 1.06-1.43), any osteoporotic fracture (RR = 1.38; 95% CI, 1.16-1.65), or hip fracture (RR = 1.68; 95% CI, 1.19-2.36). There was no significant interaction with age, BMD, or time since baseline assessment. Risk ratios were moderately but not significantly higher in men than in women, and there was no evidence for a different threshold for effect by gender. We conclude that reported intake of alcohol confers a risk of some importance beyond that explained by BMD. The validation of this risk factor on an international basis permits its use in case-finding strategies. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 292 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | <1% |
| Australia | 1 | <1% |
| Canada | 1 | <1% |
| United Kingdom | 1 | <1% |
| Denmark | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 285 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 39 | 13% |
| Student > Master | 38 | 13% |
| Student > Ph. D. Student | 36 | 12% |
| Researcher | 28 | 10% |
| Student > Postgraduate | 23 | 8% |
| Other | 61 | 21% |
| Unknown | 67 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 128 | 44% |
| Nursing and Health Professions | 22 | 8% |
| Agricultural and Biological Sciences | 15 | 5% |
| Biochemistry, Genetics and Molecular Biology | 14 | 5% |
| Engineering | 9 | 3% |
| Other | 27 | 9% |
| Unknown | 77 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2023.
All research outputs
#4,995,457
of 26,017,215 outputs
Outputs from Osteoporosis International
#810
of 3,933 outputs
Outputs of similar age
#11,458
of 77,810 outputs
Outputs of similar age from Osteoporosis International
#6
of 22 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,933 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 77,810 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.