| Title |
Genomic Disorders in Psychiatry—What Does the Clinician Need to Know?
|
|---|---|
| Published in |
Current Psychiatry Reports, September 2017
|
| DOI | 10.1007/s11920-017-0831-5 |
| Pubmed ID | |
| Authors |
Chelsea Lowther, Gregory Costain, Danielle A. Baribeau, Anne S. Bassett |
| Abstract |
The purpose of this review is to summarize the role of genomic disorders in various psychiatric conditions and to highlight important recent advances in the field that are of potential clinical relevance. Genomic disorders are caused by large rare recurrent deletions and duplications at certain chromosomal "hotspots" (e.g., 22q11.2, 16p11.2, 15q11-q13, 1q21.1, 15q13.3) across the genome. Most overlap multiple genes, affect development, and are associated with variable cognitive and other neuropsychiatric expression. Although individually rare, genomic disorders collectively account for a significant minority of intellectual disability, autism spectrum disorder, and schizophrenia. Genome-wide chromosomal microarray analysis is capable of detecting all genomic disorders in a single test, offering the first opportunity for routine clinical genetic testing in psychiatric practice. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ireland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 94 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 17 | 18% |
| Student > Ph. D. Student | 9 | 10% |
| Student > Master | 8 | 9% |
| Researcher | 7 | 7% |
| Other | 6 | 6% |
| Other | 17 | 18% |
| Unknown | 30 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 23% |
| Biochemistry, Genetics and Molecular Biology | 11 | 12% |
| Neuroscience | 8 | 9% |
| Psychology | 7 | 7% |
| Nursing and Health Professions | 4 | 4% |
| Other | 9 | 10% |
| Unknown | 33 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2021.
All research outputs
#7,859,547
of 25,595,500 outputs
Outputs from Current Psychiatry Reports
#663
of 1,287 outputs
Outputs of similar age
#113,270
of 325,887 outputs
Outputs of similar age from Current Psychiatry Reports
#23
of 37 outputs
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