| Title |
The p53 control of apoptosis and proliferation: lessons from Drosophila
|
|---|---|
| Published in |
Apoptosis, September 2014
|
| DOI | 10.1007/s10495-014-1035-7 |
| Pubmed ID | |
| Authors |
Bertrand Mollereau, Dali Ma |
| Abstract |
The canonical role of p53 in preserving genome integrity and limiting carcinogenesis has been well established. In the presence of acute DNA-damage, oncogene deregulation and other forms of cellular stress, p53 orchestrates a myriad of pleiotropic processes to repair cellular damages and maintain homeostasis. Beside these well-studied functions of p53, recent studies in Drosophila have unraveled intriguing roles of Dmp53 in promoting cell division in apoptosis-induced proliferation, enhancing fitness and proliferation of the winner cell in cell competition and coordinating growth at the organ and organismal level in the presence of stress. In this review, we describe these new functions of Dmp53 and discuss their relevance in the context of carcinogenesis. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 33% |
| United States | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 104 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 26% |
| Student > Master | 20 | 19% |
| Student > Bachelor | 15 | 14% |
| Researcher | 12 | 11% |
| Other | 2 | 2% |
| Other | 9 | 8% |
| Unknown | 20 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 39 | 37% |
| Biochemistry, Genetics and Molecular Biology | 26 | 25% |
| Chemistry | 5 | 5% |
| Medicine and Dentistry | 4 | 4% |
| Neuroscience | 3 | 3% |
| Other | 7 | 7% |
| Unknown | 22 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2015.
All research outputs
#13,313,060
of 23,577,654 outputs
Outputs from Apoptosis
#417
of 821 outputs
Outputs of similar age
#112,741
of 247,111 outputs
Outputs of similar age from Apoptosis
#5
of 10 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 821 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,111 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.