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Spider-Venom Peptides as Therapeutics

Overview of attention for article published in Toxins, December 2010
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
2 news outlets
twitter
62 X users
patent
5 patents
facebook
1 Facebook page

Citations

dimensions_citation
247 Dimensions

Readers on

mendeley
345 Mendeley
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Title
Spider-Venom Peptides as Therapeutics
Published in
Toxins, December 2010
DOI 10.3390/toxins2122851
Pubmed ID
Authors

Natalie J Saez, Sebastian Senff, Jonas E Jensen, Sing Yan Er, Volker Herzig, Lachlan D Rash, Glenn F King

Abstract

Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid subjugation of prey. Most spider venoms are dominated by disulfide-rich peptides that typically have high affinity and specificity for particular subtypes of ion channels and receptors. Spider venoms are conservatively predicted to contain more than 10 million bioactive peptides, making them a valuable resource for drug discovery. Here we review the structure and pharmacology of spider-venom peptides that are being used as leads for the development of therapeutics against a wide range of pathophysiological conditions including cardiovascular disorders, chronic pain, inflammation, and erectile dysfunction.

X Demographics

X Demographics

The data shown below were collected from the profiles of 62 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 345 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 4 1%
Brazil 3 <1%
Chile 2 <1%
Australia 1 <1%
Switzerland 1 <1%
Sudan 1 <1%
Mexico 1 <1%
United States 1 <1%
Luxembourg 1 <1%
Other 1 <1%
Unknown 329 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 63 18%
Student > Master 53 15%
Student > Ph. D. Student 45 13%
Researcher 40 12%
Student > Doctoral Student 19 6%
Other 48 14%
Unknown 77 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 105 30%
Biochemistry, Genetics and Molecular Biology 65 19%
Chemistry 26 8%
Pharmacology, Toxicology and Pharmaceutical Science 13 4%
Immunology and Microbiology 10 3%
Other 33 10%
Unknown 93 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 65. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 March 2024.
All research outputs
#666,250
of 26,017,215 outputs
Outputs from Toxins
#63
of 4,058 outputs
Outputs of similar age
#2,770
of 199,010 outputs
Outputs of similar age from Toxins
#1
of 10 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,058 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,010 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them