You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length
|
|---|---|
| Published in |
JNCI: Journal of the National Cancer Institute, September 2014
|
| DOI | 10.1093/jnci/dju267 |
| Pubmed ID | |
| Authors |
Mark M. Iles, D. Timothy Bishop, John C. Taylor, Nicholas K. Hayward, Myriam Brossard, Anne E. Cust, Alison M. Dunning, Jeffrey E. Lee, Eric K. Moses, Lars A. Akslen, Per A. Andresen, Marie-Françoise Avril, Esther Azizi, Giovanna Bianchi Scarrà, Kevin M. Brown, Tadeusz Dębniak, David E. Elder, Eitan Friedman, Paola Ghiorzo, Elizabeth M. Gillanders, Alisa M. Goldstein, Nelleke A. Gruis, Johan Hansson, Mark Harland, Per Helsing, Marko Hočevar, Veronica Höiom, Christian Ingvar, Peter A. Kanetsky, Maria Teresa Landi, Julie Lang, G. Mark Lathrop, Jan Lubiński, Rona M. Mackie, Nicholas G. Martin, Anders Molven, Grant W. Montgomery, Srdjan Novaković, Håkan Olsson, Susana Puig, Joan Anton Puig-Butille, Graham L. Radford-Smith, Juliette Randerson-Moor, Nienke van der Stoep, Remco van Doorn, David C. Whiteman, Stuart MacGregor, Karen A. Pooley, Sarah V. Ward, Graham J. Mann, Christopher I. Amos, Paul D. P. Pharoah, Florence Demenais, Matthew H. Law, Julia A. Newton Bishop, Jennifer H. Barrett |
| Abstract |
Telomere length has been associated with risk of many cancers, but results are inconsistent. Seven single nucleotide polymorphisms (SNPs) previously associated with mean leukocyte telomere length were either genotyped or well-imputed in 11108 case patients and 13933 control patients from Europe, Israel, the United States and Australia, four of the seven SNPs reached a P value under .05 (two-sided). A genetic score that predicts telomere length, derived from these seven SNPs, is strongly associated (P = 8.92x10(-9), two-sided) with melanoma risk. This demonstrates that the previously observed association between longer telomere length and increased melanoma risk is not attributable to confounding via shared environmental effects (such as ultraviolet exposure) or reverse causality. We provide the first proof that multiple germline genetic determinants of telomere length influence cancer risk. |
X Demographics
The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 21% |
| Spain | 1 | 7% |
| Germany | 1 | 7% |
| United Kingdom | 1 | 7% |
| France | 1 | 7% |
| Unknown | 7 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 50% |
| Scientists | 3 | 21% |
| Science communicators (journalists, bloggers, editors) | 2 | 14% |
| Practitioners (doctors, other healthcare professionals) | 2 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Portugal | 1 | 1% |
| Australia | 1 | 1% |
| Unknown | 90 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 25 | 27% |
| Student > Ph. D. Student | 24 | 26% |
| Student > Doctoral Student | 9 | 10% |
| Student > Bachelor | 7 | 8% |
| Student > Master | 7 | 8% |
| Other | 16 | 17% |
| Unknown | 5 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 29% |
| Biochemistry, Genetics and Molecular Biology | 25 | 27% |
| Medicine and Dentistry | 21 | 23% |
| Psychology | 3 | 3% |
| Chemistry | 2 | 2% |
| Other | 3 | 3% |
| Unknown | 12 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 74. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2015.
All research outputs
#576,959
of 25,394,764 outputs
Outputs from JNCI: Journal of the National Cancer Institute
#378
of 7,848 outputs
Outputs of similar age
#5,460
of 246,452 outputs
Outputs of similar age from JNCI: Journal of the National Cancer Institute
#9
of 140 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,848 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 21.2. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 246,452 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.