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Mendeley readers
Attention Score in Context
| Title |
Recent Advances in the Generation of Antibody–Nanomaterial Conjugates
|
|---|---|
| Published in |
Advanced Healthcare Materials, September 2017
|
| DOI | 10.1002/adhm.201700607 |
| Pubmed ID | |
| Authors |
Amal J. Sivaram, Andri Wardiana, Christopher B. Howard, Stephen M. Mahler, Kristofer J. Thurecht |
| Abstract |
Targeted nanomedicines have significantly changed the way new therapeutics are designed to treat disease. Central to successful therapeutics is the ability to control the dynamics of protein-nanomaterial interactions to enhance the therapeutic effect of the nanomedicine. The aim of this review is to illustrate the diversity and versatility of the conjugation approaches involved in the synthesis of antibody-nanoparticle conjugates, and highlight significant new advances in the field of bioconjugation. Such nanomedicines have found utility as both advanced therapeutic agents, as well as more complex imaging contrast agents that can provide both anatomical and functional information of diseased tissue. While such conjugates show significant promise as next generation targeted nanomedicines, it is recognized that there are in fact no clinically approved targeted therapeutics on the market. This fact is reflected upon within this review, and attempts are made to draw some reasoning from the complexities associated with the bioconjugation chemistry approaches that are typically utilized. Present trends, as well as future directions of next generation targeted nanomedicines are also discussed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 150 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 39 | 26% |
| Researcher | 19 | 13% |
| Student > Master | 19 | 13% |
| Student > Bachelor | 14 | 9% |
| Student > Doctoral Student | 9 | 6% |
| Other | 14 | 9% |
| Unknown | 36 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 32 | 21% |
| Biochemistry, Genetics and Molecular Biology | 19 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 14 | 9% |
| Engineering | 14 | 9% |
| Agricultural and Biological Sciences | 11 | 7% |
| Other | 18 | 12% |
| Unknown | 42 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2017.
All research outputs
#18,573,839
of 23,005,189 outputs
Outputs from Advanced Healthcare Materials
#1,895
of 2,433 outputs
Outputs of similar age
#246,018
of 321,103 outputs
Outputs of similar age from Advanced Healthcare Materials
#57
of 64 outputs
Altmetric has tracked 23,005,189 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,433 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,103 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.