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Extrapancreatic perineural invasion in pancreatic adenocarcinoma

Overview of attention for article published in Abdominal Radiology, October 2017
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Title
Extrapancreatic perineural invasion in pancreatic adenocarcinoma
Published in
Abdominal Radiology, October 2017
DOI 10.1007/s00261-017-1343-9
Pubmed ID
Authors

Bhavik N. Patel, Eric Olcott, R. Brooke Jeffrey

Abstract

Pancreatic ductal adenocarcinoma continues to be a highly lethal disease, despite advances in modern medicine. Curative surgical options continue to carry significant morbidity and offer little improvement in overall 5-year survival. Currently, imaging plays an essential role in the pre-operative evaluation of patients who are undergoing evaluation for resection. However, some pancreatic cancers have particularly aggressive biology, despite appearing resectable by conventional imaging criteria. Imaging biomarkers that serve as surrogates for tumors with such aggressive phenotype have been recently described, namely duodenal invasion and extrapancreatic perineural invasion. In this pictorial review, we will summarize key concepts of extrapancreatic perineural invasion, describe its association with a poor prognosis, and highlight the role of imaging in its detection.

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The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Other 5 15%
Student > Postgraduate 4 12%
Student > Doctoral Student 3 9%
Researcher 3 9%
Student > Master 3 9%
Other 6 18%
Unknown 9 27%
Readers by discipline Count As %
Medicine and Dentistry 13 39%
Biochemistry, Genetics and Molecular Biology 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Business, Management and Accounting 1 3%
Unspecified 1 3%
Other 4 12%
Unknown 11 33%