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Venezuelan Equine Encephalitis Virus Capsid—The Clever Caper

Overview of attention for article published in Viruses, September 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

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2 news outlets
twitter
2 X users
facebook
1 Facebook page

Citations

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33 Dimensions

Readers on

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71 Mendeley
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Title
Venezuelan Equine Encephalitis Virus Capsid—The Clever Caper
Published in
Viruses, September 2017
DOI 10.3390/v9100279
Pubmed ID
Authors

Lindsay Lundberg, Brian Carey, Kylene Kehn-Hall

Abstract

Venezuelan equine encephalitis virus (VEEV) is a New World alphavirus that is vectored by mosquitos and cycled in rodents. It can cause disease in equines and humans characterized by a febrile illness that may progress into encephalitis. Like the capsid protein of other viruses, VEEV capsid is an abundant structural protein that binds to the viral RNA and interacts with the membrane-bound glycoproteins. It also has protease activity, allowing cleavage of itself from the growing structural polypeptide during translation. However, VEEV capsid protein has additional nonstructural roles within the host cell functioning as the primary virulence factor for VEEV. VEEV capsid inhibits host transcription and blocks nuclear import in mammalian cells, at least partially due to its complexing with the host CRM1 and importin α/β1 nuclear transport proteins. VEEV capsid also shuttles between the nucleus and cytoplasm and is susceptible to inhibitors of nuclear trafficking, making it a promising antiviral target. Herein, the role of VEEV capsid in viral replication and pathogenesis will be discussed including a comparison to proteins of other alphaviruses.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 71 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 15%
Student > Bachelor 11 15%
Student > Postgraduate 8 11%
Student > Ph. D. Student 7 10%
Researcher 5 7%
Other 12 17%
Unknown 17 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 24%
Agricultural and Biological Sciences 11 15%
Immunology and Microbiology 10 14%
Veterinary Science and Veterinary Medicine 5 7%
Chemistry 2 3%
Other 5 7%
Unknown 21 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2021.
All research outputs
#1,867,305
of 23,511,526 outputs
Outputs from Viruses
#710
of 9,032 outputs
Outputs of similar age
#38,310
of 322,062 outputs
Outputs of similar age from Viruses
#9
of 111 outputs
Altmetric has tracked 23,511,526 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,032 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,062 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 111 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.