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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cholesterol Self-Powered Biosensor
|
|---|---|
| Published in |
Analytical Chemistry, September 2014
|
| DOI | 10.1021/ac501699p |
| Pubmed ID | |
| Authors |
Alina N. Sekretaryova, Valerio Beni, Mats Eriksson, Arkady A. Karyakin, Anthony P. F. Turner, Mikhail Yu. Vagin |
| Abstract |
Monitoring the cholesterol level is of great importance, especially for people with high risk of developing heart disease. Here we report on reagentless cholesterol detection in human plasma with a novel single-enzyme, membrane-free, self-powered biosensor, in which both cathodic and anodic bioelectrocatalytic reactions are powered by the same substrate. Cholesterol oxidase was immobilized in a sol-gel matrix on both the cathode and the anode. Hydrogen peroxide, a product of the enzymatic conversion of cholesterol, was electrocatalytically reduced, by the use of Prussian blue, at the cathode. In parallel, cholesterol oxidation catalyzed by mediated cholesterol oxidase occurred at the anode. The analytical performance was assessed for both electrode systems separately. The combination of the two electrodes, formed on high surface-area carbon cloth electrodes, resulted in a self-powered biosensor with enhanced sensitivity (26.0 mA M(-1) cm(-2)), compared to either of the two individual electrodes, and a dynamic range up to 4.1 mM cholesterol. Reagentless cholesterol detection with both electrochemical systems and with the self-powered biosensor was performed and the results were compared with the standard method of colorimetric cholesterol quantification. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 1% |
| Greece | 1 | <1% |
| Unknown | 135 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 19% |
| Researcher | 26 | 19% |
| Student > Master | 19 | 14% |
| Student > Bachelor | 12 | 9% |
| Student > Doctoral Student | 6 | 4% |
| Other | 24 | 17% |
| Unknown | 25 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 39 | 28% |
| Engineering | 18 | 13% |
| Materials Science | 13 | 9% |
| Biochemistry, Genetics and Molecular Biology | 11 | 8% |
| Agricultural and Biological Sciences | 8 | 6% |
| Other | 18 | 13% |
| Unknown | 31 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2023.
All research outputs
#6,671,604
of 23,572,442 outputs
Outputs from Analytical Chemistry
#7,535
of 26,828 outputs
Outputs of similar age
#65,196
of 240,535 outputs
Outputs of similar age from Analytical Chemistry
#75
of 376 outputs
Altmetric has tracked 23,572,442 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 26,828 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,535 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 376 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.