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Patient-Derived Mouse Models of Cancer

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Cover of 'Patient-Derived Mouse Models of Cancer'

Table of Contents

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    Book Overview
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    Chapter 1 In Memoriam: Jørgen Rygaard (1934–2016), Father of Patient-Derived Mouse Models of Cancer and Modern Cancer Research
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    Chapter 2 The Revival of Patient-Derived Xenograft Mouse Models of Cancer: Way Back to the Future
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    Chapter 3 Patient-Derived Xenograft Models for Human Cancer: The Freiburg Experience
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    Chapter 4 From Ectopic to Orthotopic Tumor Grafting Sites: Evidence for a Critical Role of the Host Tissue Microenvironment for the Actual Expression of the Malignant Phenotype
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    Chapter 5 The Effects of the Organ Microenvironment on Metastatic Cell Gene Signatures
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    Chapter 6 Techniques for Surgical Orthotopic Implantation of Human Tumors to Immunodeficient Mice
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    Chapter 7 The First Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer: Cancer of the Colon, Pancreas, Lung, Breast, Ovary, and Mesothelioma
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    Chapter 8 Patient-Derived Xenograft Models of Prostate Cancer
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    Chapter 9 Patient-Derived Mouse Models of Sarcoma
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    Chapter 10 Cervical Cancer PDOX Models
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    Chapter 11 The Use of Pediatric Patient-Derived Xenografts for Identifying Novel Agents and Combinations
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    Chapter 12 Development of Orthotopic and Spontaneous Metastatic Human Tumor Xenograft Models for Experimental Therapeutics
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    Chapter 13 Use of Patient-Derived Orthotopic Xenografts (PDOX) to Evaluate Transformative Cancer Therapeutics
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    Chapter 14 Fluorescent Protein-Expressing Transgenic Nude Mice as Hosts for Patient Tumors
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    Chapter 15 Fluorescence Imaging of Tumors in Human Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models
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    Chapter 16 The Use of Patient-Derived Orthotopic Xenograft (PDOX) Models to Develop Curative Fluorescence-Guided Surgery of Cancer
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    Chapter 17 Molecular Characteristics of Patient-Derived Tumor Xenografts: Similarities to Patient Tumors and Relevance for Biomarker Discovery
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    Chapter 18 Synergy of Patient-Derived Orthotopic Xenografts (PDOX) Models and Molecular Profiling for Optimal Therapy
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    Chapter 19 3D Cell Culture Models
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    Chapter 20 Why Patient-Derived Mouse Models Need to Be Orthotopic
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    Chapter 21 Afterward: The Future of Patient-Derived Models of Cancer
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Title
Patient-Derived Mouse Models of Cancer
Published by
Humana Press, January 2017
DOI 10.1007/978-3-319-57424-0
ISBNs
978-3-31-957424-0, 978-3-31-957423-3
Editors

Robert M. Hoffman

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 21%
Student > Master 2 14%
Student > Ph. D. Student 1 7%
Student > Doctoral Student 1 7%
Researcher 1 7%
Other 1 7%
Unknown 5 36%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 14%
Medicine and Dentistry 2 14%
Biochemistry, Genetics and Molecular Biology 1 7%
Mathematics 1 7%
Psychology 1 7%
Other 3 21%
Unknown 4 29%