| Title |
Macrophage mTORC1 disruption reduces inflammation and insulin resistance in obese mice
|
|---|---|
| Published in |
Diabetologia, August 2014
|
| DOI | 10.1007/s00125-014-3350-5 |
| Pubmed ID | |
| Authors |
Hongfeng Jiang, Marit Westerterp, Chunjiong Wang, Yi Zhu, Ding Ai |
| Abstract |
Inflammatory factors secreted by macrophages play an important role in obesity-related insulin resistance. Being at the crossroads of a nutrient-hormonal signalling network, the mammalian target of rapamycin complex 1 (mTORC1) controls important functions in the regulation of energy balance and peripheral metabolism. However, the role of macrophage mTORC1 in insulin resistance is still unclear. In the current study, we investigated the physiological role of macrophage mTORC1 in regulating inflammation and insulin sensitivity. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 93 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 24 | 25% |
| Student > Ph. D. Student | 20 | 21% |
| Student > Master | 9 | 9% |
| Student > Bachelor | 7 | 7% |
| Student > Doctoral Student | 5 | 5% |
| Other | 10 | 11% |
| Unknown | 20 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 22 | 23% |
| Agricultural and Biological Sciences | 19 | 20% |
| Medicine and Dentistry | 14 | 15% |
| Immunology and Microbiology | 7 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Other | 6 | 6% |
| Unknown | 25 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2014.
All research outputs
#21,445,966
of 23,940,793 outputs
Outputs from Diabetologia
#5,043
of 5,195 outputs
Outputs of similar age
#200,334
of 234,653 outputs
Outputs of similar age from Diabetologia
#42
of 49 outputs
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