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In Utero Exposure and Breast Cancer Development: an Epigenetic Perspective

Overview of attention for article published in Journal of Environmental Pathology, Toxicology & Oncology, January 2014
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Title
In Utero Exposure and Breast Cancer Development: an Epigenetic Perspective
Published in
Journal of Environmental Pathology, Toxicology & Oncology, January 2014
DOI 10.1615/jenvironpatholtoxicoloncol.2014011005
Pubmed ID
Authors

Jacob Hill, Wendy Hodsdon

Abstract

The ubiquitous and detrimental disease of breast cancer requires continual research into new and alternative forms of treatment and prevention. The emerging field of epigenetics is beginning to unfold an array of contemporary approaches to reduce the risk and improve the clinical approach to breast cancer. The information contained in this non-systematic review highlights and expands on the estrogen-based model of breast cancer epigenetics to provide an overview of epigenetic alterations induced by nutrition and environmental exposure. The majority of evidence suggests that various sources of excess estrogen correlate to future breast cancer development. In addition, maternal macro- and micronutrient balance appear to play a role in genomic regulation, and preliminary data suggest that specific superfoods, such as blueberries, have a protective epigenetic effect. Identifying the influence of environmental toxicants, hormonal exposure, maternal nutrition, and maternal disease on fetal epigenetics may have potential for development of new therapeutic approaches for the prevention of breast cancer.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 5 24%
Researcher 4 19%
Student > Master 3 14%
Student > Ph. D. Student 3 14%
Other 2 10%
Other 3 14%
Unknown 1 5%
Readers by discipline Count As %
Medicine and Dentistry 9 43%
Biochemistry, Genetics and Molecular Biology 5 24%
Nursing and Health Professions 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Sports and Recreations 1 5%
Other 1 5%
Unknown 3 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 October 2014.
All research outputs
#22,760,732
of 25,377,790 outputs
Outputs from Journal of Environmental Pathology, Toxicology & Oncology
#173
of 213 outputs
Outputs of similar age
#280,470
of 319,301 outputs
Outputs of similar age from Journal of Environmental Pathology, Toxicology & Oncology
#9
of 10 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 213 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,301 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one.