| Title |
White Matter Microstructure of the Human Mirror Neuron System is Related to Symptom Severity in Adults with Autism
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, October 2017
|
| DOI | 10.1007/s10803-017-3332-9 |
| Pubmed ID | |
| Authors |
Odette Fründt, Robert Schulz, Daniel Schöttle, Bastian Cheng, Götz Thomalla, Hanna Braaß, Christos Ganos, Nicole David, Ina Peiker, Andreas K. Engel, Tobias Bäumer, Alexander Münchau |
| Abstract |
Mirror neuron system (MNS) dysfunctions might underlie deficits in autism spectrum disorders (ASD). Diffusion tensor imaging based probabilistic tractography was conducted in 15 adult ASD patients and 13 matched, healthy controls. Fractional anisotropy (FA) was quantified to assess group differences in tract-related white matter microstructure of both the classical MNS route (mediating "emulation") and the alternative temporo-frontal route (mediating "mimicry"). Multiple linear regression was used to investigate structure-function relationships between MNS connections and ASD symptom severity. There were no significant group differences in tract-related FA indicating an intact classical MNS in ASD. Direct temporo-frontal connections could not be reconstructed challengeing the concept of multiple routes for imitation. Tract-related FA of right-hemispheric parieto-frontal connections was negatively related to autism symptom severity. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 71 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 17% |
| Researcher | 12 | 17% |
| Student > Bachelor | 7 | 10% |
| Student > Doctoral Student | 5 | 7% |
| Student > Master | 5 | 7% |
| Other | 9 | 13% |
| Unknown | 21 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 13 | 18% |
| Psychology | 12 | 17% |
| Medicine and Dentistry | 6 | 8% |
| Linguistics | 2 | 3% |
| Social Sciences | 2 | 3% |
| Other | 8 | 11% |
| Unknown | 28 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2017.
All research outputs
#21,376,200
of 23,867,274 outputs
Outputs from Journal of Autism and Developmental Disorders
#4,711
of 5,240 outputs
Outputs of similar age
#287,460
of 327,785 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#110
of 130 outputs
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