Title |
The circuitry of abulia: Insights from functional connectivity MRI
|
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Published in |
NeuroImage: Clinical, September 2014
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DOI | 10.1016/j.nicl.2014.09.012 |
Pubmed ID | |
Authors |
J.S. Siegel, A.Z. Snyder, N.V. Metcalf, R.P. Fucetola, C.D. Hacker, J.S. Shimony, G.L. Shulman, M. Corbetta |
Abstract |
Functional imaging and lesion studies have associated willed behavior with the anterior cingulate cortex (ACC). Abulia is a syndrome characterized by apathy and deficiency of motivated behavior. Abulia is most frequently associated with ACC damage, but also occurs following damage to subcortical nuclei (striatum, globus pallidus, thalamic nuclei). We present resting state functional connectivity MRI (fcMRI) data from an individual who suffered a stroke leading to abulia. We hypothesized that, although structural imaging revealed no damage to the patient's ACC, fcMRI would uncover aberrant function in this region and in the relevant cortical networks. |
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United Kingdom | 2 | 13% |
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Spain | 1 | 6% |
Unknown | 9 | 56% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 12 | 75% |
Scientists | 3 | 19% |
Practitioners (doctors, other healthcare professionals) | 1 | 6% |
Mendeley readers
Geographical breakdown
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Mexico | 1 | 1% |
Spain | 1 | 1% |
United States | 1 | 1% |
Unknown | 91 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 15 | 16% |
Student > Ph. D. Student | 13 | 14% |
Student > Master | 13 | 14% |
Other | 8 | 9% |
Student > Postgraduate | 7 | 7% |
Other | 21 | 22% |
Unknown | 17 | 18% |
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Neuroscience | 19 | 20% |
Psychology | 16 | 17% |
Agricultural and Biological Sciences | 5 | 5% |
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Other | 6 | 6% |
Unknown | 23 | 24% |