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Multiple system atrophy is not caused by C9orf72 hexanucleotide repeat expansions

Overview of attention for article published in Neurobiology of Aging, September 2014
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Title
Multiple system atrophy is not caused by C9orf72 hexanucleotide repeat expansions
Published in
Neurobiology of Aging, September 2014
DOI 10.1016/j.neurobiolaging.2014.08.033
Pubmed ID
Authors

Sonja W. Scholz, Elisa Majounie, Tamas Revesz, Janice L. Holton, Michael S. Okun, Henry Houlden, Andrew B. Singleton

Abstract

Multiple system atrophy (MSA) is a fatal neurodegenerative disorder of unknown etiology that presents with variable combinations of progressive ataxia, parkinsonism, and autonomic instability. Pathologic expansion of a hexanucleotide repeat in the C9orf72 gene has been demonstrated to cause neurodegeneration with diverse neurologic presentations. To test the hypothesis whether pathologic expansions in C9orf72 are a cause of MSA, we undertook genetic screening in 100 neuropathologically confirmed cases. No pathologic repeat expansions were detected suggesting that MSA is not a C9orf72-related neurodegenerative disease.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 29%
Researcher 3 9%
Professor > Associate Professor 3 9%
Student > Doctoral Student 2 6%
Student > Bachelor 2 6%
Other 8 24%
Unknown 6 18%
Readers by discipline Count As %
Medicine and Dentistry 8 24%
Neuroscience 6 18%
Biochemistry, Genetics and Molecular Biology 3 9%
Nursing and Health Professions 2 6%
Agricultural and Biological Sciences 1 3%
Other 2 6%
Unknown 12 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2014.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Neurobiology of Aging
#4,224
of 4,418 outputs
Outputs of similar age
#214,306
of 250,094 outputs
Outputs of similar age from Neurobiology of Aging
#95
of 107 outputs
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