Title |
Surveillance or metastasis-directed Therapy for OligoMetastatic Prostate cancer recurrence (STOMP): study protocol for a randomized phase II trial
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Published in |
BMC Cancer, September 2014
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DOI | 10.1186/1471-2407-14-671 |
Pubmed ID | |
Authors |
Karel Decaestecker, Gert De Meerleer, Filip Ameye, Valerie Fonteyne, Bieke Lambert, Steven Joniau, Louke Delrue, Ignace Billiet, Wim Duthoy, Sarah Junius, Wouter Huysse, Nicolaas Lumen, Piet Ost |
Abstract |
Metastases-directed therapy (MDT) with surgery or stereotactic body radiotherapy (SBRT) is emerging as a new treatment option for prostate cancer (PCa) patients with a limited number of metastases (≤3) at recurrence - so called "oligometastases". One of the goals of this approach is to delay the start of palliative androgen deprivation therapy (ADT), with its negative impact on quality of life. However, the lack of a control group, selection bias and the use of adjuvant androgen deprivation therapy prevent strong conclusions from published studies.The aim of this multicenter randomized phase II trial is to assess the impact of MTD on the start of palliative ADT compared to patients undergoing active surveillance. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 3 | 38% |
United States | 1 | 13% |
Spain | 1 | 13% |
Belgium | 1 | 13% |
United Kingdom | 1 | 13% |
Unknown | 1 | 13% |
Demographic breakdown
Type | Count | As % |
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Scientists | 4 | 50% |
Members of the public | 2 | 25% |
Science communicators (journalists, bloggers, editors) | 1 | 13% |
Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Chile | 1 | <1% |
Germany | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 176 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 29 | 16% |
Student > Ph. D. Student | 19 | 11% |
Student > Master | 19 | 11% |
Student > Bachelor | 17 | 9% |
Other | 14 | 8% |
Other | 44 | 25% |
Unknown | 37 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 94 | 53% |
Nursing and Health Professions | 8 | 4% |
Agricultural and Biological Sciences | 4 | 2% |
Immunology and Microbiology | 3 | 2% |
Biochemistry, Genetics and Molecular Biology | 3 | 2% |
Other | 15 | 8% |
Unknown | 52 | 29% |