Title |
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
|
---|---|
Published in |
New England Journal of Medicine, March 2005
|
DOI | 10.1056/nejmoa043330 |
Pubmed ID | |
Authors |
Roger Stupp, Warren P Mason, Martin J van den Bent, Michael Weller, Barbara Fisher, Martin J B Taphoorn, Karl Belanger, Alba A Brandes, Christine Marosi, Ulrich Bogdahn, Jürgen Curschmann, Robert C Janzer, Samuel K Ludwin, Thierry Gorlia, Anouk Allgeier, Denis Lacombe, J Gregory Cairncross, Elizabeth Eisenhauer, René O Mirimanoff |
Abstract |
Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to the extent feasible, followed by adjuvant radiotherapy. In this trial we compared radiotherapy alone with radiotherapy plus temozolomide, given concomitantly with and after radiotherapy, in terms of efficacy and safety. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 14 | 34% |
India | 3 | 7% |
Spain | 3 | 7% |
United Kingdom | 2 | 5% |
South Africa | 1 | 2% |
Saudi Arabia | 1 | 2% |
Denmark | 1 | 2% |
New Zealand | 1 | 2% |
Canada | 1 | 2% |
Other | 0 | 0% |
Unknown | 14 | 34% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 29 | 71% |
Scientists | 6 | 15% |
Practitioners (doctors, other healthcare professionals) | 4 | 10% |
Science communicators (journalists, bloggers, editors) | 2 | 5% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 39 | <1% |
Japan | 10 | <1% |
United Kingdom | 8 | <1% |
Germany | 7 | <1% |
France | 7 | <1% |
Netherlands | 6 | <1% |
Italy | 6 | <1% |
Brazil | 5 | <1% |
Switzerland | 5 | <1% |
Other | 32 | <1% |
Unknown | 4755 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 724 | 15% |
Researcher | 653 | 13% |
Student > Bachelor | 560 | 11% |
Student > Master | 536 | 11% |
Student > Doctoral Student | 381 | 8% |
Other | 852 | 17% |
Unknown | 1174 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 1345 | 28% |
Biochemistry, Genetics and Molecular Biology | 607 | 12% |
Agricultural and Biological Sciences | 516 | 11% |
Neuroscience | 254 | 5% |
Engineering | 146 | 3% |
Other | 660 | 14% |
Unknown | 1352 | 28% |