| Title |
Progress of hearing loss in neurofibromatosis type 2: implications for future management
|
|---|---|
| Published in |
European Archives of Oto-Rhino-Laryngology, October 2014
|
| DOI | 10.1007/s00405-014-3317-7 |
| Pubmed ID | |
| Authors |
Georgios Kontorinis, Jaya Nichani, Simon R. Freeman, Scott A. Rutherford, Samantha Mills, Andrew T. King, Deborah Mawman, Sue Huson, Martin O’Driscoll, D. Gareth Evans, Simon K. W. Lloyd |
| Abstract |
The objective of this study was to describe changes in hearing over time in patients with neurofibromatosis type 2 (NF2) treated conservatively. A retrospective case review was conducted in a tertiary referral centre. Pure tone audiometry, speech discrimination scores, serviceable hearing (American Academy of Otolaryngology class A or B) and measurement of vestibular schwannoma (VS) size on magnetic resonance imaging were evaluated in 56 patients (89 ears) with NF2 with at least one conservatively managed VS. Over a mean follow-up period of 7 years (range 0.8-21 years) pure tone average thresholds increased gradually with a mean annual rate of 1.3 dB for the right ear (p = 0.0003) and 2 dB for the left ear (p = 0.0009). Speech discrimination scores dropped with an average annual rate of 1.3 and 0.34 % in the right and left ear, respectively. Patients maintained serviceable hearing for an average of 7.6 years (range 2.7-19.3 years). The average annual VS growth was 0.4 mm without any correlation with hearing loss. There was a correlation between patients' age and pure tone threshold increase (p < 0.05 for both ears). In this selected population of patients with NF2, hearing threshold increases were very slow. In NF2 patients with indolently behaving tumours, serviceable hearing can be maintained for a significant length of time, making conservative management an attractive option. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 46 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 15% |
| Student > Bachelor | 7 | 15% |
| Student > Doctoral Student | 7 | 15% |
| Other | 5 | 11% |
| Researcher | 5 | 11% |
| Other | 7 | 15% |
| Unknown | 9 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 38% |
| Nursing and Health Professions | 6 | 13% |
| Neuroscience | 5 | 11% |
| Engineering | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Other | 4 | 9% |
| Unknown | 10 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2014.
All research outputs
#17,728,060
of 22,765,347 outputs
Outputs from European Archives of Oto-Rhino-Laryngology
#1,469
of 3,060 outputs
Outputs of similar age
#171,780
of 255,128 outputs
Outputs of similar age from European Archives of Oto-Rhino-Laryngology
#26
of 75 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,060 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,128 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.