| Title |
Intramyocellular lipid and glycogen content are reduced following resistance exercise in untrained healthy males
|
|---|---|
| Published in |
European Journal of Applied Physiology, December 2005
|
| DOI | 10.1007/s00421-005-0118-0 |
| Pubmed ID | |
| Authors |
René Koopman, Ralph J. F. Manders, Richard A. M. Jonkers, Gabby B. J. Hul, Harm Kuipers, Luc J. C. van Loon |
| Abstract |
Resistance exercise has recently been shown to improve whole-body insulin sensitivity in healthy males. Whether this is accompanied by an exercise-induced decline in skeletal muscle glycogen and/or lipid content remains to be established. In the present study, we determined fibre-type-specific changes in skeletal muscle substrate content following a single resistance exercise session. After an overnight fast, eight untrained healthy lean males participated in a approximately 45 min resistance exercise session. Muscle biopsies were collected before, following cessation of exercise, and after 30 and 120 min of post-exercise recovery. Subjects remained fasted throughout the test. Conventional light and (immuno)fluorescence microscopy were applied to assess fibre-type-specific changes in intramyocellular triacylglycerol (IMTG) and glycogen content. A significant 27+/-7% net decline in IMTG content was observed in the type I muscle fibres (P<0.05), with no net changes in the type IIa and IIx fibres. Muscle glycogen content decreased with 23+/-6, 40+/-7 and 44+/-7% in the type I, IIa and IIx muscle fibres, respectively (P<0.05). Fibre-type-specific changes in intramyocellular lipid and/or glycogen content correlated well with muscle fibre-type oxidative capacity. During post-exercise recovery, type I muscle fibre lipid content returned to pre-exercise levels within 120 min. No changes in muscle glycogen content were observed during recovery. We conclude that intramyocellular lipid and glycogen stores are readily used during resistance exercise and this is likely associated with the reported increase in whole-body insulin sensitivity following resistance exercise. |
X Demographics
The data shown below were collected from the profiles of 71 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 18% |
| United Kingdom | 6 | 8% |
| Spain | 4 | 6% |
| Japan | 3 | 4% |
| Canada | 2 | 3% |
| Netherlands | 2 | 3% |
| India | 1 | 1% |
| Taiwan | 1 | 1% |
| Venezuela, Bolivarian Republic of | 1 | 1% |
| Other | 7 | 10% |
| Unknown | 31 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 44 | 62% |
| Scientists | 15 | 21% |
| Practitioners (doctors, other healthcare professionals) | 11 | 15% |
| Unknown | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| United States | 2 | 1% |
| Brazil | 2 | 1% |
| Germany | 1 | <1% |
| Denmark | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 166 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 33 | 19% |
| Student > Bachelor | 26 | 15% |
| Student > Ph. D. Student | 22 | 13% |
| Researcher | 19 | 11% |
| Student > Postgraduate | 11 | 6% |
| Other | 31 | 18% |
| Unknown | 33 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 64 | 37% |
| Agricultural and Biological Sciences | 24 | 14% |
| Medicine and Dentistry | 19 | 11% |
| Biochemistry, Genetics and Molecular Biology | 9 | 5% |
| Nursing and Health Professions | 8 | 5% |
| Other | 14 | 8% |
| Unknown | 37 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 47. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2022.
All research outputs
#892,412
of 25,374,917 outputs
Outputs from European Journal of Applied Physiology
#260
of 4,345 outputs
Outputs of similar age
#1,831
of 171,986 outputs
Outputs of similar age from European Journal of Applied Physiology
#2
of 21 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,345 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one has done particularly well, scoring higher than 94% of its peers.
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