Title |
How Low to Go With Glucose, Cholesterol, and Blood Pressure in Primary Prevention of CVD
|
---|---|
Published in |
JACC, October 2017
|
DOI | 10.1016/j.jacc.2017.09.001 |
Pubmed ID | |
Authors |
Kimberly N. Hong, Valentin Fuster, Robert S. Rosenson, Clive Rosendorff, Deepak L. Bhatt |
Abstract |
Diabetes, hyperlipidemia, and hypertension are modifiable risk factors that predict cardiovascular disease events. The effect of these risk factors on incident cardiovascular disease increases with progressively higher levels of glucose, low-density lipoprotein cholesterol, and blood pressure. The thresholds for initiating treatment of these modifiable risk factors and the optimal goals of risk factor modification are a focus of primary prevention research. Although an aggressive approach is appealing, adverse events may occur, and potential physiological barriers may exist. This paper discusses primary prevention of coronary heart disease that may be achieved through modification of diabetes, hyperlipidemia, and hypertension by summarizing current guidelines and pertinent clinical trial data from intervention trials that included a primary prevention cohort. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 26 | 19% |
Spain | 13 | 9% |
Mexico | 9 | 6% |
Venezuela, Bolivarian Republic of | 9 | 6% |
Colombia | 4 | 3% |
Peru | 4 | 3% |
Ecuador | 3 | 2% |
Brazil | 2 | 1% |
Croatia | 2 | 1% |
Other | 17 | 12% |
Unknown | 50 | 36% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 91 | 65% |
Practitioners (doctors, other healthcare professionals) | 24 | 17% |
Scientists | 19 | 14% |
Science communicators (journalists, bloggers, editors) | 5 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 186 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 22 | 12% |
Student > Ph. D. Student | 20 | 11% |
Student > Bachelor | 18 | 10% |
Other | 18 | 10% |
Student > Postgraduate | 15 | 8% |
Other | 35 | 19% |
Unknown | 58 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 67 | 36% |
Nursing and Health Professions | 12 | 6% |
Biochemistry, Genetics and Molecular Biology | 8 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
Agricultural and Biological Sciences | 5 | 3% |
Other | 17 | 9% |
Unknown | 71 | 38% |