Title |
Isolation and extraction of antimicrobial substances against oral bacteria from lemon peel
|
---|---|
Published in |
Journal of Food Science and Technology, March 2011
|
DOI | 10.1007/s13197-011-0330-3 |
Pubmed ID | |
Authors |
Yoshiaki Miyake, Masanori Hiramitsu |
Abstract |
We have isolated 4 antibacterial substances that were active against the oral bacteria that cause dental caries and periodontitis, such as Streptococcus mutans, Prevotella intermedia, and Porphyromonas gingivalis, from lemon peel, a waste product in the citrus industry. The isolated substances were identified as 8-geranyloxypsolaren, 5-geranyloxypsolaren, 5-geranyloxy-7-methoxycoumarin, and phloroglucinol 1-β-D-glucopyranoside (phlorin) upon structural analyses. Among these, 8-Geranyloxypsolaren, 5-geranyloxypsolaren, and 5-geranyloxy-7-methoxycoumarin exhibited high antibacterial activity. These 3 compounds were effectively extracted using ethanol and n-hexane, whereas phlorin was extracted with water. Further, the above 3 compounds were present in lemon essential oil and abundantly present in the residue produced upon the cooling treatment of concentrated lemon essential oil. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 1% |
Unknown | 88 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 14 | 16% |
Student > Master | 12 | 13% |
Researcher | 6 | 7% |
Student > Postgraduate | 6 | 7% |
Student > Ph. D. Student | 6 | 7% |
Other | 16 | 18% |
Unknown | 29 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 20% |
Medicine and Dentistry | 9 | 10% |
Chemistry | 9 | 10% |
Biochemistry, Genetics and Molecular Biology | 6 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
Other | 13 | 15% |
Unknown | 30 | 34% |