Title |
Human Chorionic Villous Mesenchymal Stem Cells Modify the Functions of Human Dendritic Cells, and Induce an Anti-Inflammatory Phenotype in CD1+ Dendritic Cells
|
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Published in |
Stem Cell Reviews and Reports, October 2014
|
DOI | 10.1007/s12015-014-9562-8 |
Pubmed ID | |
Authors |
F. M. Abomaray, M. A. Al Jumah, B. Kalionis, A. S. AlAskar, S. Al Harthy, D. Jawdat, A. Al Khaldi, A. Alkushi, B. A. Knawy, M. H. Abumaree |
Abstract |
Mesenchymal stem cells derived from the chorionic villi of human term placenta (pMSCs) have drawn considerable interest because of their multipotent differentiation potential and their immunomodulatory capacity. These properties are the foundation for their clinical application in the fields of stem cell transplantation and regenerative medicine. Previously, we showed that pMSCs induce an anti-inflammatory phenotype in human macrophages. In this study, we determined whether pMSCs modify the differentiation and maturation of human monocytes into dendritic cells (DCs). The consequences on dendritic function and on T cell proliferation were also investigated. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 18% |
Student > Ph. D. Student | 5 | 11% |
Student > Doctoral Student | 5 | 11% |
Student > Master | 4 | 9% |
Other | 3 | 7% |
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Unknown | 13 | 30% |
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Nursing and Health Professions | 1 | 2% |
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Unknown | 15 | 34% |