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Mendeley readers
Attention Score in Context
| Title |
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing
|
|---|---|
| Published in |
Current Opinion in Genetics & Development, August 2014
|
| DOI | 10.1016/j.gde.2014.06.009 |
| Pubmed ID | |
| Authors |
Francesca Rossiello, Utz Herbig, Maria Pia Longhese, Marzia Fumagalli, Fabrizio d’Adda di Fagagna |
| Abstract |
The DNA damage response (DDR) orchestrates DNA repair and halts cell cycle. If damage is not resolved, cells can enter into an irreversible state of proliferative arrest called cellular senescence. Organismal ageing in mammals is associated with accumulation of markers of cellular senescence and DDR persistence at telomeres. Since the vast majority of the cells in mammals are non-proliferating, how do they age? Are telomeres involved? Also oncogene activation causes cellular senescence due to altered DNA replication and DDR activation in particular at the telomeres. Is there a common mechanism shared among apparently distinct types of cellular senescence? And what is the role of telomeric DNA damage? |
Mendeley readers
The data shown below were compiled from readership statistics for 170 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | 1% |
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| Netherlands | 1 | <1% |
| Unknown | 165 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 36 | 21% |
| Researcher | 28 | 16% |
| Student > Bachelor | 15 | 9% |
| Student > Master | 13 | 8% |
| Other | 8 | 5% |
| Other | 27 | 16% |
| Unknown | 43 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 48 | 28% |
| Agricultural and Biological Sciences | 37 | 22% |
| Medicine and Dentistry | 11 | 6% |
| Immunology and Microbiology | 5 | 3% |
| Neuroscience | 4 | 2% |
| Other | 19 | 11% |
| Unknown | 46 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2014.
All research outputs
#4,101,849
of 25,374,917 outputs
Outputs from Current Opinion in Genetics & Development
#365
of 1,740 outputs
Outputs of similar age
#38,423
of 242,846 outputs
Outputs of similar age from Current Opinion in Genetics & Development
#10
of 33 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,740 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,846 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.