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Comparative analysis of mean retinal thickness measured using SD-OCT in normal young or old age and glaucomatous eyes

Overview of attention for article published in International Ophthalmology, October 2017
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Title
Comparative analysis of mean retinal thickness measured using SD-OCT in normal young or old age and glaucomatous eyes
Published in
International Ophthalmology, October 2017
DOI 10.1007/s10792-017-0744-7
Pubmed ID
Authors

Jun Won Jang, Myung Won Lee, Kyong Jin Cho

Abstract

To evaluate changes in macular thickness, ganglion cell layer/inner plexiform layer (GCL/IPL) thickness, and retinal nerve fiber layer (RNFL) thickness in normal eyes and glaucomatous eyes using spectral domain optical coherence tomography (SD-OCT). We enrolled 89 eyes (all left eyes), including 45 (of 45 patients) eyes with glaucoma and 44 (of 44 patients) normal eyes. The data from macular measurements using spectral domain optical coherence tomography were analyzed according to groups divided by age and glaucoma status. The macular thickness analysis, GCL/IPL thickness, and RNFL thickness values determined by SD-OCT scans were compared among the groups. Mean macular thickness decreased significantly with age or glaucoma. Mean GCL/IPL thickness decreased significantly in glaucomatous eyes in all sectors but did not decrease with age. Mean RNFL thickness, which was divided into four quadrants (superior, nasal, inferior, and temporal), decreased significantly in glaucomatous eyes at all quadrants and decreased in the temporal quadrant with age in non-glaucomatous eyes. No significant differences were detected between eyes with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) in all sectors of mean GCL/IPL thickness, RNFL thickness, and macular thickness. No significant difference in mean thickness was detected between eyes with NTG and POAG. Some of the sectors of RNFL thickness decreased with age or glaucoma. GCL/IPL thickness, however, decreased in glaucomatous eyes but not with age. Therefore, GCL/IPL thickness is less influenced by age when monitoring patients with glaucoma or suspect glaucoma.

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Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 21%
Student > Master 2 14%
Other 1 7%
Professor 1 7%
Unknown 7 50%
Readers by discipline Count As %
Medicine and Dentistry 4 29%
Nursing and Health Professions 2 14%
Biochemistry, Genetics and Molecular Biology 1 7%
Unknown 7 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2017.
All research outputs
#20,450,513
of 23,006,268 outputs
Outputs from International Ophthalmology
#674
of 1,042 outputs
Outputs of similar age
#283,335
of 324,848 outputs
Outputs of similar age from International Ophthalmology
#9
of 16 outputs
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