| Title |
Epigenetic regulators: multifunctional proteins modulating hypoxia-inducible factor-α protein stability and activity
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, October 2017
|
| DOI | 10.1007/s00018-017-2684-9 |
| Pubmed ID | |
| Authors |
Weibo Luo, Yingfei Wang |
| Abstract |
The hypoxia-inducible factor (HIF) is a heterodimeric transcription factor governing a transcriptional program in response to reduced O2 availability in metazoans. It contributes to physiology and pathogenesis of many human diseases through its downstream target genes. Emerging studies have shown that the transcriptional activity of HIF is highly regulated at multiple levels and the epigenetic regulators are essential for HIF-mediated transactivation. In this review, we will discuss the comprehensive regulation of HIF transcriptional activity by different types of epigenetic regulators. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 43 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 23% |
| Researcher | 7 | 16% |
| Student > Bachelor | 6 | 14% |
| Student > Doctoral Student | 5 | 12% |
| Student > Master | 2 | 5% |
| Other | 3 | 7% |
| Unknown | 10 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 13 | 30% |
| Agricultural and Biological Sciences | 9 | 21% |
| Environmental Science | 1 | 2% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Nursing and Health Professions | 1 | 2% |
| Other | 5 | 12% |
| Unknown | 13 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2018.
All research outputs
#19,201,293
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#3,458
of 4,151 outputs
Outputs of similar age
#252,294
of 327,717 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#54
of 69 outputs
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We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.