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Long-Term Outcomes With Transcatheter Aortic Valve Replacement in Women Compared With Men Evidence From a Meta-Analysis

Overview of attention for article published in JACC: Cardiovascular Interventions, October 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

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3 news outlets
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79 X users
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3 Facebook pages

Citations

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104 Dimensions

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81 Mendeley
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Title
Long-Term Outcomes With Transcatheter Aortic Valve Replacement in Women Compared With Men Evidence From a Meta-Analysis
Published in
JACC: Cardiovascular Interventions, October 2017
DOI 10.1016/j.jcin.2017.08.015
Pubmed ID
Authors

Marwan Saad, Ramez Nairooz, Naga Venkata K. Pothineni, Ahmed Almomani, Swathi Kovelamudi, Partha Sardar, Marcelo Katz, Mohamed Abdel-Wahab, Sripal Bangalore, Neal S. Kleiman, Peter C. Block, J. Dawn Abbott

Abstract

This study sought to examine long-term outcomes with transcatheter aortic valve replacement (TAVR) in women versus men. TAVR is commonly performed in women. Previous studies have shown conflicting results with respect to sex differences in outcomes with TAVR. In addition, short-term outcomes have primarily been reported. Electronic search was performed until March 2017 for studies reporting outcomes with TAVR in women versus men. Random effects DerSimonian-Laird risk ratios were calculated. Outcomes included all-cause mortality and major cardiovascular events at short- (30 days) and long-term (>1 year) follow-up. Seventeen studies (8 TAVR registries; 47,188 patients; 49.4% women) were analyzed. Women were older but exhibited fewer comorbidities. At 30 days, women had more bleeding (p < 0.001), vascular complications (p < 0.001), and stroke/transient ischemic attack (p = 0.02), without difference in all-cause (p = 0.19) or cardiovascular mortality (p = 0.91) compared with men. However, female sex was associated with lower all-cause mortality at 1 year (risk ratio: 0.85; 95% confidence interval: 0.79 to 0.91; p < 0.001), and longest available follow-up (mean 3.28 ± 1.04 years; risk ratio: 0.86; 95% confidence interval: 0.81 to 0.92; p < 0.001), potentially caused by less moderate/severe aortic insufficiency (p = 0.001), and lower cardiovascular mortality (p = 0.009). The female survival advantage remained consistent across multiple secondary analyses. The risk of stroke, moderate/severe aortic insufficiency, and all-cause mortality seemed to vary based on the type of valve used; however, without significant subgroup interactions. Despite a higher upfront risk of complications, women derive a better long-term survival after TAVR compared with men.

X Demographics

X Demographics

The data shown below were collected from the profiles of 79 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 81 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 10 12%
Researcher 9 11%
Student > Ph. D. Student 5 6%
Student > Master 5 6%
Other 4 5%
Other 12 15%
Unknown 36 44%
Readers by discipline Count As %
Medicine and Dentistry 34 42%
Nursing and Health Professions 2 2%
Agricultural and Biological Sciences 1 1%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Social Sciences 1 1%
Other 1 1%
Unknown 41 51%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 67. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2020.
All research outputs
#638,234
of 25,382,440 outputs
Outputs from JACC: Cardiovascular Interventions
#152
of 4,032 outputs
Outputs of similar age
#13,516
of 336,554 outputs
Outputs of similar age from JACC: Cardiovascular Interventions
#3
of 90 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,032 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,554 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.