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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Recent advances in large-scale production of monoclonal antibodies and related proteins
|
|---|---|
| Published in |
Trends in Biotechnology, March 2010
|
| DOI | 10.1016/j.tibtech.2010.02.001 |
| Pubmed ID | |
| Authors |
Abhinav A. Shukla, Jörg Thömmes |
| Abstract |
The rapid development of high-yielding and robust manufacturing processes for monoclonal antibodies is an area of significant focus in the biopharmaceutical landscape. Advances in mammalian cell culture have taken titers to beyond the 5 g/l mark. Platform approaches to downstream process development have become widely established. Continuous evolution of these platforms is occurring as experience with a wider range of products is accrued. The increased cell culture productivity has shifted the attention of bioprocess development to operations downstream of the production bioreactor. This has rejuvenated interest in the use of non-chromatographic separation processes. Here, we review the current state-of-the-art industrial production processes, focusing on downstream technologies, for antibodies and antibody-related products and discuss future avenues for evolution. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Turkey | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,134 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | <1% |
| United Kingdom | 6 | <1% |
| Mexico | 4 | <1% |
| Brazil | 3 | <1% |
| Italy | 2 | <1% |
| Canada | 2 | <1% |
| Germany | 1 | <1% |
| Australia | 1 | <1% |
| Austria | 1 | <1% |
| Other | 9 | <1% |
| Unknown | 1097 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 214 | 19% |
| Student > Bachelor | 204 | 18% |
| Student > Master | 203 | 18% |
| Researcher | 139 | 12% |
| Student > Doctoral Student | 48 | 4% |
| Other | 133 | 12% |
| Unknown | 193 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 253 | 22% |
| Biochemistry, Genetics and Molecular Biology | 198 | 17% |
| Engineering | 162 | 14% |
| Chemical Engineering | 107 | 9% |
| Chemistry | 64 | 6% |
| Other | 137 | 12% |
| Unknown | 213 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2023.
All research outputs
#3,274,899
of 25,374,917 outputs
Outputs from Trends in Biotechnology
#601
of 2,856 outputs
Outputs of similar age
#12,584
of 103,048 outputs
Outputs of similar age from Trends in Biotechnology
#1
of 12 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,856 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,048 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.