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Fructose ingestion acutely stimulates circulating FGF21 levels in humans

Overview of attention for article published in Molecular Metabolism, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

news
1 news outlet
twitter
14 X users
googleplus
2 Google+ users

Citations

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183 Dimensions

Readers on

mendeley
183 Mendeley
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Title
Fructose ingestion acutely stimulates circulating FGF21 levels in humans
Published in
Molecular Metabolism, October 2014
DOI 10.1016/j.molmet.2014.09.008
Pubmed ID
Authors

Jody R. Dushay, Elena Toschi, Emilie K. Mitten, Ffolliott M. Fisher, Mark A. Herman, Eleftheria Maratos-Flier

Abstract

Fibroblast growth factor 21 (FGF21) is a hormone with pleiotropic metabolic activities which, in rodents, is robustly regulated by fasting and ketogenic diets. In contrast, similar dietary interventions have either no or minimal effects on circulating FGF21 in humans. Moreover, no intervention or dietary challenge has been shown to acutely stimulate circulating FGF21 in either humans or animals. Recent animal data suggest that the transcription factor Carbohydrate Responsive-Element Binding Protein (ChREBP) stimulates hepatic FGF21 expression and that fructose may activate hepatic ChREBP more robustly than glucose. Here, we examined whether fructose ingestion can acutely stimulate FGF21 in humans.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 183 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 1%
United States 2 1%
Switzerland 1 <1%
Spain 1 <1%
Sweden 1 <1%
Unknown 176 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 33 18%
Student > Master 22 12%
Student > Ph. D. Student 20 11%
Student > Bachelor 18 10%
Other 11 6%
Other 37 20%
Unknown 42 23%
Readers by discipline Count As %
Medicine and Dentistry 47 26%
Biochemistry, Genetics and Molecular Biology 32 17%
Agricultural and Biological Sciences 23 13%
Neuroscience 7 4%
Nursing and Health Professions 5 3%
Other 19 10%
Unknown 50 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 September 2023.
All research outputs
#1,976,949
of 26,017,215 outputs
Outputs from Molecular Metabolism
#269
of 1,634 outputs
Outputs of similar age
#21,778
of 271,593 outputs
Outputs of similar age from Molecular Metabolism
#2
of 15 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,634 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.8. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,593 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.