Title |
Nuclear localization of the mitochondrial ncRNAs in normal and cancer cells
|
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Published in |
Cellular Oncology, February 2011
|
DOI | 10.1007/s13402-011-0018-8 |
Pubmed ID | |
Authors |
Eduardo Landerer, Jaime Villegas, Veronica A. Burzio, Luciana Oliveira, Claudio Villota, Constanza Lopez, Franko Restovic, Ronny Martinez, Octavio Castillo, Luis O. Burzio |
Abstract |
We have previously shown a differential expression of a family of mitochondrial ncRNAs in normal and cancer cells. Normal proliferating cells and cancer cells express the sense mitochondrial ncRNA (SncmtRNA). In addition, while normal proliferating cells express two antisense mitochondrial ncRNAs (ASncmtRNAs-1 and -2), these transcripts seem to be universally down-regulated in cancer cells. In situ hybridization (ISH) of some normal and cancer tissues reveals nuclear localization of these transcripts suggesting that they are exported from mitochondria. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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United Kingdom | 1 | 2% |
Germany | 1 | 2% |
Unknown | 52 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 14 | 26% |
Researcher | 10 | 19% |
Other | 5 | 9% |
Student > Postgraduate | 4 | 7% |
Student > Master | 3 | 6% |
Other | 8 | 15% |
Unknown | 10 | 19% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 13 | 24% |
Medicine and Dentistry | 4 | 7% |
Unspecified | 2 | 4% |
Immunology and Microbiology | 1 | 2% |
Other | 2 | 4% |
Unknown | 12 | 22% |