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Cardiac Nonmyocyte Cell Functions and Crosstalks in Response to Cardiotoxic Drugs

Overview of attention for article published in Oxidative Medicine & Cellular Longetivity, October 2017
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  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

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3 X users

Citations

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14 Dimensions

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22 Mendeley
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Title
Cardiac Nonmyocyte Cell Functions and Crosstalks in Response to Cardiotoxic Drugs
Published in
Oxidative Medicine & Cellular Longetivity, October 2017
DOI 10.1155/2017/1089359
Pubmed ID
Authors

Jessica Gambardella, Bruno Trimarco, Guido Iaccarino, Daniela Sorriento

Abstract

The discovery of the molecular mechanisms involved in the cardiac responses to anticancer drugs represents the current goal of cardio-oncology research. The oxidative stress has a pivotal role in cardiotoxic responses, affecting the function of all types of cardiac cells, and their functional crosstalks. Generally, cardiomyocytes are the main target of research studies on cardiotoxicity, but recently the contribution of the other nonmyocyte cardiac cells is becoming of growing interest. This review deals with the role of oxidative stress, induced by anticancer drugs, in cardiac nonmyocyte cells (fibroblasts, vascular cells, and immune cells). The alterations of functional interplays among these cardiac cells are discussed, as well. These interesting recent findings increase the knowledge about cardiotoxicity and suggest new molecular targets for both diagnosis and therapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 18%
Professor > Associate Professor 4 18%
Researcher 4 18%
Student > Bachelor 3 14%
Professor 1 5%
Other 2 9%
Unknown 4 18%
Readers by discipline Count As %
Medicine and Dentistry 5 23%
Biochemistry, Genetics and Molecular Biology 4 18%
Pharmacology, Toxicology and Pharmaceutical Science 4 18%
Agricultural and Biological Sciences 2 9%
Chemistry 1 5%
Other 0 0%
Unknown 6 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2018.
All research outputs
#15,097,241
of 25,382,440 outputs
Outputs from Oxidative Medicine & Cellular Longetivity
#1,368
of 3,628 outputs
Outputs of similar age
#174,355
of 337,929 outputs
Outputs of similar age from Oxidative Medicine & Cellular Longetivity
#34
of 92 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,628 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,929 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.