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ALPPS as a salvage procedure after insufficient future liver remnant hypertrophy following portal vein occlusion

Overview of attention for article published in HPB: The Official Journal of the International Hepato Pacreato Biliary Association, September 2017
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Title
ALPPS as a salvage procedure after insufficient future liver remnant hypertrophy following portal vein occlusion
Published in
HPB: The Official Journal of the International Hepato Pacreato Biliary Association, September 2017
DOI 10.1016/j.hpb.2017.08.013
Pubmed ID
Authors

Marcelo Enne, Erik Schadde, Bergthór Björnsson, Roberto Hernandez Alejandro, Klaus Steinbruck, Eduardo Viana, Ricardo Robles Campos, Massimo Malago, Pierre-Alain Clavien, Eduardo De Santibanes, Brice Gayet, ALPPS Registry Group

Abstract

A minimum future liver remnant (FLR) of 30% is required to avoid post hepatectomy liver failure (PHLF). Portal vein occlusion (PVO) is the main strategy to induce hypertrophy of the FLR, but some patients will not reach sufficient FLR hypertrophy to enable resection. Recently ALPPS has emerged as a "Salvage Procedure" for PVO failure. The aim of this study was to report the short term outcomes of ALPPS following PVO failure. A retrospective analysis of patients enrolled within the international ALPPS Registry between October 2012 and November 2015 (NCT01924741) was performed. Patients with documented PVO failure were included. The outcomes reported included feasibility, FLR growth rate and safety of ALPPS. Complications were recorded as per Clavien-Dindo classification. From 510 patients enrolled in the Registry there were 22 patients with previous PVO failure. Two patients were excluded due to missing data and twenty patients were analysed. All of them completed the proposed ALPPS with a medium FLR increase of 88% (23-115%) between two stages and no 90-day mortality. In experienced centers, ALPPS following PVO failure is feasible and safe. The FLR hypertrophy was similar to other ALPPS series. ALPPS is a potential rescue strategy after PVO failure.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Professor 6 20%
Researcher 5 17%
Student > Postgraduate 4 13%
Student > Master 4 13%
Other 3 10%
Other 5 17%
Unknown 3 10%
Readers by discipline Count As %
Medicine and Dentistry 25 83%
Nursing and Health Professions 1 3%
Unknown 4 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2018.
All research outputs
#16,051,091
of 25,382,440 outputs
Outputs from HPB: The Official Journal of the International Hepato Pacreato Biliary Association
#606
of 1,248 outputs
Outputs of similar age
#184,219
of 323,485 outputs
Outputs of similar age from HPB: The Official Journal of the International Hepato Pacreato Biliary Association
#7
of 18 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,248 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,485 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.