You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Oral delivery of nanoparticle-based vaccines
|
|---|---|
| Published in |
Expert Review of Vaccines, August 2014
|
| DOI | 10.1586/14760584.2014.936852 |
| Pubmed ID | |
| Authors |
Nirmal Marasini, Mariusz Skwarczynski, Istvan Toth |
| Abstract |
Most infectious diseases are caused by pathogenic infiltrations from the mucosal tract. Therefore, vaccines delivered to the mucosal tissues can mimic natural infections and provide protection at the first site of infection. Thus, mucosal, especially, oral delivery is becoming the most preferred mode of vaccination. However, oral vaccines have to overcome several barriers such as the extremely low pH of the stomach, the presence of proteolytic enzymes and bile salts as well as low permeability in the intestine. Several formulations based on nanoparticle strategies are currently being explored to prepare stable oral vaccine formulations. This review briefly discusses several molecular mechanisms involved in intestinal immune cell activation and various aspects of oral nanoparticle-based vaccine design that should be considered for improved mucosal and systemic immune responses. |
Mendeley readers
The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Unknown | 113 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 21% |
| Researcher | 20 | 18% |
| Student > Master | 20 | 18% |
| Student > Bachelor | 10 | 9% |
| Lecturer | 3 | 3% |
| Other | 10 | 9% |
| Unknown | 27 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 16 | 14% |
| Immunology and Microbiology | 14 | 12% |
| Agricultural and Biological Sciences | 11 | 10% |
| Chemistry | 10 | 9% |
| Biochemistry, Genetics and Molecular Biology | 8 | 7% |
| Other | 19 | 17% |
| Unknown | 36 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2023.
All research outputs
#8,305,323
of 25,481,734 outputs
Outputs from Expert Review of Vaccines
#749
of 1,615 outputs
Outputs of similar age
#77,889
of 247,310 outputs
Outputs of similar age from Expert Review of Vaccines
#19
of 37 outputs
Altmetric has tracked 25,481,734 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 1,615 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,310 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.