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Checkpoint inhibitor-induced uveitis: a case series

Overview of attention for article published in Graefe's Archive for Clinical and Experimental Ophthalmology, October 2017
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Title
Checkpoint inhibitor-induced uveitis: a case series
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology, October 2017
DOI 10.1007/s00417-017-3835-2
Pubmed ID
Authors

Christopher D. Conrady, Marissa Larochelle, Paula Pecen, Alan Palestine, Akbar Shakoor, Ajay Singh

Abstract

Checkpoint inhibitors are now a common treatment modality for metastatic cancer. In this manuscript, we describe the clinical features and management of autoimmune non-infectious uveitis induced by this class of drugs. Seven patients undergoing checkpoint inhibitor treatment for metastatic cancer from uveitis practices at three tertiary referral centers. All seven patients developed various severities of ocular inflammatory disease while taking checkpoint inhibitors for metastatic disease. Checkpoint inhibitors may induce autoimmune uveitis. Ocular complaints should prompt an early evaluation by an ophthalmologist.

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The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Other 9 20%
Student > Bachelor 5 11%
Student > Postgraduate 4 9%
Student > Master 3 7%
Researcher 3 7%
Other 5 11%
Unknown 17 37%
Readers by discipline Count As %
Medicine and Dentistry 16 35%
Nursing and Health Professions 4 9%
Immunology and Microbiology 2 4%
Arts and Humanities 1 2%
Agricultural and Biological Sciences 1 2%
Other 2 4%
Unknown 20 43%