Title |
Checkpoint inhibitor-induced uveitis: a case series
|
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Published in |
Graefe's Archive for Clinical and Experimental Ophthalmology, October 2017
|
DOI | 10.1007/s00417-017-3835-2 |
Pubmed ID | |
Authors |
Christopher D. Conrady, Marissa Larochelle, Paula Pecen, Alan Palestine, Akbar Shakoor, Ajay Singh |
Abstract |
Checkpoint inhibitors are now a common treatment modality for metastatic cancer. In this manuscript, we describe the clinical features and management of autoimmune non-infectious uveitis induced by this class of drugs. Seven patients undergoing checkpoint inhibitor treatment for metastatic cancer from uveitis practices at three tertiary referral centers. All seven patients developed various severities of ocular inflammatory disease while taking checkpoint inhibitors for metastatic disease. Checkpoint inhibitors may induce autoimmune uveitis. Ocular complaints should prompt an early evaluation by an ophthalmologist. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 46 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 9 | 20% |
Student > Bachelor | 5 | 11% |
Student > Postgraduate | 4 | 9% |
Student > Master | 3 | 7% |
Researcher | 3 | 7% |
Other | 5 | 11% |
Unknown | 17 | 37% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 16 | 35% |
Nursing and Health Professions | 4 | 9% |
Immunology and Microbiology | 2 | 4% |
Arts and Humanities | 1 | 2% |
Agricultural and Biological Sciences | 1 | 2% |
Other | 2 | 4% |
Unknown | 20 | 43% |