Title |
Validation of oral fluid samples to monitor serological changes to Plasmodium falciparum: An observational study in southern Zambia
|
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Published in |
Malaria Journal, June 2011
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DOI | 10.1186/1475-2875-10-162 |
Pubmed ID | |
Authors |
Alexis P Chidi, Sandra Chishimba, Tamaki Kobayashi, Harry Hamapumbu, Sungano Mharakurwa, Philip E Thuma, William J Moss |
Abstract |
In formerly endemic areas where malaria transmission has declined, levels of population immunity to Plasmodium falciparum provide information on continued malaria transmission and potentially susceptible populations. Traditional techniques for measuring serological responses to P. falciparum antigens use plasma or dried blood spots (DBS). These invasive procedures pose a biohazard and may be unacceptable to communities if performed frequently. The use of oral fluid (OF) samples to detect antibodies to P. falciparum antigens may be a more acceptable strategy to monitor changes in population immunity. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 7% |
Pakistan | 1 | 3% |
France | 1 | 3% |
Canada | 1 | 3% |
United Kingdom | 1 | 3% |
Unknown | 23 | 79% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 28% |
Researcher | 4 | 14% |
Student > Master | 4 | 14% |
Other | 3 | 10% |
Student > Doctoral Student | 2 | 7% |
Other | 6 | 21% |
Unknown | 2 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 28% |
Medicine and Dentistry | 5 | 17% |
Immunology and Microbiology | 2 | 7% |
Environmental Science | 1 | 3% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 7 | 24% |
Unknown | 5 | 17% |