| Title |
Effect of structured physical activity and nutritional supplementation on physical function in mobility-limited older adults: Results from the VIVE2 randomized trial
|
|---|---|
| Published in |
The journal of nutrition, health & aging, November 2017
|
| DOI | 10.1007/s12603-017-0936-x |
| Pubmed ID | |
| Authors |
Roger A. Fielding, T.G. Travison, D.R. Kirn, A. Koochek, K.F. Reid, Å. von Berens, H. Zhu, S.C. Folta, J.M. Sacheck, M.E. Nelson, C.K. Liu, A.C. Åberg, M. Nydahl, M. Lilja, T. Gustafsson, T. Cederholm |
| Abstract |
The interactions between nutritional supplementation and physical activity on changes in physical function among older adults remain unclear. The primary objective of this study was to examine the impact of nutritional supplementation plus structured physical activity on 400M walk capacity in mobility-limited older adults across two sites (Boston, USA and Stockholm, Sweden). All subjects participated in a physical activity program (3x/week for 24 weeks), involving walking, strength, balance, and flexibility exercises. Subjects were randomized to a daily nutritional supplement (150kcal, 20g whey protein, 800 IU vitamin D) or placebo (30kcal, non-nutritive). Participants were recruited from urban communities at 2 field centers in Boston MA USA and Stockholm SWE. Mobility-limited (Short Physical Performance Battery (SPPB) ≤9) and vitamin D insufficient (serum 25(OH) D 9 - 24 ng/ml) older adults were recruited for this study. Primary outcome was gait speed assessed by the 400M walk. 149 subjects were randomized into the study (mean age=77.5±5.4; female=46.3%; mean SPPB= 7.9±1.2; mean 25(OH)D=18.7±6.4 ng/ml). Adherence across supplement and placebo groups was similar (86% and 88%, respectively), and was also similar across groups for the physical activity intervention (75% and 72%, respectively). Both groups demonstrated an improvement in gait speed with no significant difference between those who received the nutritional supplement compared to the placebo (0.071 and 0.108 m/s, respectively (p=0.06)). Similar effects in physical function were observed using the SPPB. Serum 25(OH)D increased in supplemented group compared to placebo 7.4 ng/ml versus 1.3 ng/ml respectively. Results suggest improved gait speed following physical activity program with no further improvement with added nutritional supplementation. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 183 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 183 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 22 | 12% |
| Student > Bachelor | 17 | 9% |
| Researcher | 16 | 9% |
| Student > Ph. D. Student | 12 | 7% |
| Student > Doctoral Student | 10 | 5% |
| Other | 29 | 16% |
| Unknown | 77 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 28 | 15% |
| Medicine and Dentistry | 19 | 10% |
| Sports and Recreations | 16 | 9% |
| Social Sciences | 8 | 4% |
| Biochemistry, Genetics and Molecular Biology | 6 | 3% |
| Other | 18 | 10% |
| Unknown | 88 | 48% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2017.
All research outputs
#8,573,050
of 25,728,855 outputs
Outputs from The journal of nutrition, health & aging
#1,076
of 2,003 outputs
Outputs of similar age
#130,272
of 341,761 outputs
Outputs of similar age from The journal of nutrition, health & aging
#25
of 44 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 2,003 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,761 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.