| Title |
Safety and possible effects of low-intensity resistance training associated with partial blood flow restriction in polymyositis and dermatomyositis
|
|---|---|
| Published in |
Arthritis Research & Therapy, October 2014
|
| DOI | 10.1186/s13075-014-0473-5 |
| Pubmed ID | |
| Authors |
Melina Andrade Mattar, Bruno Gualano, Luiz Augusto Perandini, Samuel Katsuyuki Shinjo, Fernanda Rodrigues Lima, Ana Lúcia Sá-Pinto, Hamilton Roschel |
| Abstract |
IntroductionOur aim was to evaluate the safety and efficacy of a low-intensity resistance training program combined with partial blow flow restriction (BFR training) in a cohort of patients with polymyositis (PM) and dermatomyositis (DM).MethodsIn total, 13 patients with PM and DM completed a 12-week twice a week low-intensity (that is, 30% one-repetition-maximum (1RM)) resistance exercise training program combined with partial blood flow restriction (BFR). Assessments of muscle strength, physical function, quadriceps cross sectional (CSA) area, health-related quality of life, and clinical and laboratory parameters were assessed at baseline and after the intervention.ResultsThe BFR training program was effective in increasing the maximal dynamic strength in both the leg-press (19.6%, P <0.001) and knee-extension exercises (25.2% P <0.001), as well as in the timed-stands (15.1%, P <0.001) and timed-up-and-go test (¿4.5%, P =0.002). Quadriceps CSA was also significantly increased after the intervention (4.57%, P =0.01). Similarly, all of the components of the Short Form-36 Health Survey, the Health Assessment Questionnaire scores, and the patient- and physician reported Visual Analogue Scale were significantly improved after training (P <0.05). Importantly, no clinical evidence or any other self-reported adverse event were found. Laboratory parameters (creatine kinase and aldolase) were also unchanged (P >0.05) after the intervention.ConclusionsWe demonstrated that a 12-week supervised low-intensity resistance training program associated with partial blood flow restriction may be safe and effective in improving muscle strength and function as well as muscle mass and health-related quality of life in patients with PM and DM.Trial registrationClinicaltrials.gov NCT01501019. Registered November 29, 2011. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 25% |
| United Kingdom | 2 | 25% |
| Saudi Arabia | 1 | 13% |
| Australia | 1 | 13% |
| Malaysia | 1 | 13% |
| Unknown | 1 | 13% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 75% |
| Scientists | 2 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 325 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | <1% |
| Colombia | 1 | <1% |
| Unknown | 322 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 48 | 15% |
| Student > Master | 44 | 14% |
| Student > Ph. D. Student | 29 | 9% |
| Student > Postgraduate | 23 | 7% |
| Researcher | 22 | 7% |
| Other | 55 | 17% |
| Unknown | 104 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 64 | 20% |
| Sports and Recreations | 59 | 18% |
| Nursing and Health Professions | 48 | 15% |
| Agricultural and Biological Sciences | 9 | 3% |
| Biochemistry, Genetics and Molecular Biology | 8 | 2% |
| Other | 22 | 7% |
| Unknown | 115 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 May 2017.
All research outputs
#6,847,541
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#1,437
of 3,381 outputs
Outputs of similar age
#70,144
of 273,492 outputs
Outputs of similar age from Arthritis Research & Therapy
#21
of 59 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 57% of its peers.
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