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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Measurement of average decoding rates of the 61 sense codons in vivo
|
|---|---|
| Published in |
eLife, October 2014
|
| DOI | 10.7554/elife.03735 |
| Pubmed ID | |
| Authors |
Justin Gardin, Rukhsana Yeasmin, Alisa Yurovsky, Ying Cai, Steve Skiena, Bruce Futcher |
| Abstract |
Most amino acids can be encoded by several synonymous codons, which are used at unequal frequencies. The significance of unequal codon usage remains unclear. One hypothesis is that frequent codons are translated relatively rapidly. However, there is little direct, in vivo evidence regarding codon-specific translation rates. Here, we generate high-coverage data using ribosome profiling in yeast, analyze using a novel algorithm, and deduce events at the A and P-sites of the ribosome. Different codons are decoded at different rates in the A-site. In general frequent codons are decoded more quickly than rare codons, and AT-rich codons are decoded more quickly than GC-rich codons. At the P-site, proline is slow in forming peptide bonds. We also apply our algorithm to short footprints from a different conformation of the ribosome, and find strong, amino-acid specific (not codon-specific) effects that may reflect interactions with the exit tunnel of the ribosome. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 25% |
| United States | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 256 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 2% |
| United Kingdom | 3 | 1% |
| Germany | 1 | <1% |
| Sweden | 1 | <1% |
| Israel | 1 | <1% |
| Czechia | 1 | <1% |
| Netherlands | 1 | <1% |
| New Zealand | 1 | <1% |
| France | 1 | <1% |
| Other | 2 | <1% |
| Unknown | 238 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 71 | 28% |
| Researcher | 52 | 20% |
| Student > Master | 25 | 10% |
| Student > Doctoral Student | 14 | 5% |
| Student > Postgraduate | 12 | 5% |
| Other | 43 | 17% |
| Unknown | 39 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 95 | 37% |
| Biochemistry, Genetics and Molecular Biology | 90 | 35% |
| Chemistry | 10 | 4% |
| Computer Science | 5 | 2% |
| Engineering | 4 | 2% |
| Other | 12 | 5% |
| Unknown | 40 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2015.
All research outputs
#2,762,042
of 23,577,654 outputs
Outputs from eLife
#7,209
of 14,362 outputs
Outputs of similar age
#32,786
of 262,024 outputs
Outputs of similar age from eLife
#72
of 179 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,362 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 36.8. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,024 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 179 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.