| Title |
Treatment of critical-sized bone defects: clinical and tissue engineering perspectives
|
|---|---|
| Published in |
European Journal of Orthopaedic Surgery & Traumatology, October 2017
|
| DOI | 10.1007/s00590-017-2063-0 |
| Pubmed ID | |
| Authors |
Erika Roddy, Malcolm R. DeBaun, Adam Daoud-Gray, Yunzhi P. Yang, Michael J. Gardner |
| Abstract |
Critical-sized bone defects are defined as those that will not heal spontaneously within a patient's lifetime. Current treatment options include vascularized bone grafts, distraction osteogenesis, and the induced membrane technique. The induced membrane technique is an increasingly utilized method with favorable results including high rates of union. Tissue engineering holds promise in the treatment of large bone defects due to advancement of stem cell biology, novel biomaterials, and 3D bioprinting. In this review, we provide an overview of the current operative treatment strategies of critical-sized bone defects as well as the current state of tissue engineering for such defects. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 412 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 412 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 64 | 16% |
| Student > Bachelor | 52 | 13% |
| Student > Master | 46 | 11% |
| Researcher | 29 | 7% |
| Student > Doctoral Student | 19 | 5% |
| Other | 52 | 13% |
| Unknown | 150 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 67 | 16% |
| Engineering | 67 | 16% |
| Biochemistry, Genetics and Molecular Biology | 33 | 8% |
| Materials Science | 31 | 8% |
| Agricultural and Biological Sciences | 11 | 3% |
| Other | 36 | 9% |
| Unknown | 167 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2020.
All research outputs
#14,957,976
of 23,007,053 outputs
Outputs from European Journal of Orthopaedic Surgery & Traumatology
#310
of 882 outputs
Outputs of similar age
#194,395
of 328,548 outputs
Outputs of similar age from European Journal of Orthopaedic Surgery & Traumatology
#7
of 10 outputs
Altmetric has tracked 23,007,053 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 882 research outputs from this source. They receive a mean Attention Score of 2.2. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,548 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.