| Title |
Longitudinal Immune Responses and Gene Expression Profiles in Type 1 Leprosy Reactions
|
|---|---|
| Published in |
Journal of Clinical Immunology, December 2013
|
| DOI | 10.1007/s10875-013-9979-x |
| Pubmed ID | |
| Authors |
Annemieke Geluk, Krista E. van Meijgaarden, Louis Wilson, Kidist Bobosha, Jolien J. van der Ploeg-van Schip, Susan J. F. van den Eeden, Edwin Quinten, Karin Dijkman, Kees L. M. C. Franken, Elisabeth M. Haisma, Mariëlle C. Haks, Colette L. M. van Hees, Tom H. M. Ottenhoff |
| Abstract |
Leprosy, a chronic disease initiated by Mycobacterium leprae, is often complicated by acute inflammatory reactions. Although such episodes occur in at least 50% of all leprosy patients and may cause irreversible nerve damage, no laboratory tests are available for early diagnosis or prediction of reactions. Since immune- and genetic host factors are critical in leprosy reactions, we hypothesize that identification of host-derived biomarkers correlated to leprosy reactions can provide the basis for new tests to facilitate timely diagnosis and treatment thereby helping to prevent tissue damage. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 1% |
| Unknown | 74 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 20% |
| Student > Master | 12 | 16% |
| Student > Doctoral Student | 9 | 12% |
| Student > Bachelor | 9 | 12% |
| Other | 5 | 7% |
| Other | 8 | 11% |
| Unknown | 17 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 23% |
| Agricultural and Biological Sciences | 12 | 16% |
| Biochemistry, Genetics and Molecular Biology | 8 | 11% |
| Immunology and Microbiology | 6 | 8% |
| Nursing and Health Professions | 5 | 7% |
| Other | 9 | 12% |
| Unknown | 18 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2014.
All research outputs
#20,241,019
of 22,768,097 outputs
Outputs from Journal of Clinical Immunology
#1,252
of 1,556 outputs
Outputs of similar age
#265,831
of 306,179 outputs
Outputs of similar age from Journal of Clinical Immunology
#13
of 17 outputs
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