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Macrophage Migration Inhibitory Factor Down‐Regulates the RANKL–RANK Signaling Pathway by Activating Lyn Tyrosine Kinase in Mouse Models

Overview of attention for article published in Arthritis & Rheumatology, August 2014
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Title
Macrophage Migration Inhibitory Factor Down‐Regulates the RANKL–RANK Signaling Pathway by Activating Lyn Tyrosine Kinase in Mouse Models
Published in
Arthritis & Rheumatology, August 2014
DOI 10.1002/art.38723
Pubmed ID
Authors

Se Hwan Mun, Dongmyung Oh, Sun‐Kyeong Lee

Abstract

Macrophage migration inhibitory factor (MIF) is an important modulator of innate and adaptive immunity as well as local inflammatory responses. We previously reported that MIF down-regulated osteoclastogenesis through a mechanism that requires CD74. The aim of the current study was to examine whether MIF modulates osteoclastogenesis through Lyn phosphorylation, and whether down-regulation of RANKL-mediated signaling requires the association of CD74, CD44, and Lyn.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 9%
China 1 9%
Unknown 9 82%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 36%
Student > Doctoral Student 1 9%
Student > Bachelor 1 9%
Professor 1 9%
Student > Master 1 9%
Other 2 18%
Unknown 1 9%
Readers by discipline Count As %
Medicine and Dentistry 4 36%
Biochemistry, Genetics and Molecular Biology 2 18%
Agricultural and Biological Sciences 2 18%
Immunology and Microbiology 1 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 9%
Other 0 0%
Unknown 1 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2014.
All research outputs
#22,029,081
of 24,577,646 outputs
Outputs from Arthritis & Rheumatology
#2,741
of 2,967 outputs
Outputs of similar age
#206,026
of 241,399 outputs
Outputs of similar age from Arthritis & Rheumatology
#72
of 73 outputs
Altmetric has tracked 24,577,646 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,967 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 21.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,399 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.