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MicroRNA and Cancer

Overview of attention for book
Cover of 'MicroRNA and Cancer'

Table of Contents

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    Book Overview
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    Chapter 1 Noncoding RNAs in DNA Damage Response: Opportunities for Cancer Therapeutics
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    Chapter 2 MicroRNAs in Breast Cancer: Diagnostic and Therapeutic Potential
  4. Altmetric Badge
    Chapter 3 Involvement of miRNAs and Pseudogenes in Cancer
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    Chapter 4 MicroRNAs Reprogram Tumor Immune Response
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    Chapter 5 Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like Gene Expression, RNA Editing, and MicroRNAs Regulation
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    Chapter 6 MicroRNAs Change the Landscape of Cancer Resistance
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    Chapter 7 MicroRNA, Noise, and Gene Expression Regulation
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    Chapter 8 Deep Sequencing Reveals a MicroRNA Expression Signature in Triple-Negative Breast Cancer
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    Chapter 9 Detection of Plasma MicroRNA Signature in Osteosarcoma Patients
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    Chapter 10 Identification of E6/E7-Dependent MicroRNAs in HPV-Positive Cancer Cells
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    Chapter 11 Combination of Anti-miRNAs Oligonucleotides with Low Amounts of Chemotherapeutic Agents for Pancreatic Cancer Therapy
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    Chapter 12 Evaluation of MicroRNA Delivery In Vivo
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    Chapter 13 Angiogenesis Analysis by In Vitro Coculture Assays in Transwell Chambers in Ovarian Cancer
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    Chapter 14 Application of Individual qPCR Performance Parameters for Quality Control of Circulating MicroRNA Data
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    Chapter 15 Construction of Multi-Potent MicroRNA Sponge and Its Functional Evaluation
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    Chapter 16 MicroRNA Sequencing Data Analysis Toolkits
Attention for Chapter 7: MicroRNA, Noise, and Gene Expression Regulation
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Chapter title
MicroRNA, Noise, and Gene Expression Regulation
Chapter number 7
Book title
MicroRNA and Cancer
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7435-1_7
Pubmed ID
Book ISBNs
978-1-4939-7433-7, 978-1-4939-7435-1
Authors

Wei Wu, Wu, Wei

Abstract

Gene regulatory network that determines the cellular functions exhibits stochastic fluctuations, or "noise," in different layers. Noise has begun to be appreciated for many previously unrecognized functions in important cellular activities. In fact, molecular noise is unavoidable in both microbial and eukaryotic cells, the feedback system is established evolutionally to reduce noise or optimize the noise for cellular homeostasis. The small noncoding RNAs, particularly, microNRAs, post-transcriptionally and negatively regulate gene expressions. MicroRNAs function as a novel layer to buffer noise level, and stabilize mRNA and protein level to maintain normal cellular function. Furthermore, the changing of microRNA expression levels may increase the stochastic fluctuation leading to abnormal cellular function, even diseases.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 38%
Researcher 3 38%
Student > Doctoral Student 1 13%
Student > Master 1 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 38%
Nursing and Health Professions 1 13%
Agricultural and Biological Sciences 1 13%
Physics and Astronomy 1 13%
Unknown 2 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2017.
All research outputs
#18,575,277
of 23,007,053 outputs
Outputs from Methods in molecular biology
#7,962
of 13,159 outputs
Outputs of similar age
#330,463
of 442,275 outputs
Outputs of similar age from Methods in molecular biology
#950
of 1,498 outputs
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So far Altmetric has tracked 13,159 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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