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Analogues of Pseudomonas aeruginosa signalling molecules to tackle infections

Overview of attention for article published in Organic and Biomolecular Chemistry, January 2018
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  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

Mentioned by

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4 X users

Citations

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36 Dimensions

Readers on

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46 Mendeley
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Title
Analogues of Pseudomonas aeruginosa signalling molecules to tackle infections
Published in
Organic and Biomolecular Chemistry, January 2018
DOI 10.1039/c7ob02395b
Pubmed ID
Authors

Eoin Ó Muimhneacháin, F. Jerry Reen, Fergal O'Gara, Gerard P. McGlacken

Abstract

The emergence of antibiotic resistance coupled with the lack of investment by pharmaceutical companies necessitates a new look at how we tackle bacterial infections. An intriguing tactic is the interruption of bacterial communication systems. This non-biocidal approach would circumvent the evolutionary pressure on bacteria to mutate and develop resistance. In many pathogenic microorganisms, communication systems, collectively termed quorum sensing (QS), have been observed to control a number of bacterial behaviours including expression of virulence factors and the development of biofilms. QS signalling molecules and their biomimetics, therefore, represent a rational target for the disruption of cooperative behaviour and thus the development of novel antimicrobial strategies. Herein we review recent developments towards the interference of Pseudomonas aeruginosa QS using signalling molecules and their mimetics.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 20%
Student > Ph. D. Student 8 17%
Student > Bachelor 7 15%
Student > Doctoral Student 6 13%
Student > Postgraduate 3 7%
Other 6 13%
Unknown 7 15%
Readers by discipline Count As %
Chemistry 9 20%
Biochemistry, Genetics and Molecular Biology 8 17%
Immunology and Microbiology 6 13%
Agricultural and Biological Sciences 5 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 6 13%
Unknown 10 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2017.
All research outputs
#14,782,360
of 25,756,911 outputs
Outputs from Organic and Biomolecular Chemistry
#4,082
of 6,872 outputs
Outputs of similar age
#223,756
of 452,073 outputs
Outputs of similar age from Organic and Biomolecular Chemistry
#152
of 351 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,872 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 452,073 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 351 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.