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Effect of the Increasing Use of Piperacillin/Tazobactam on the Incidence of Vancomycin-Resistant Enterococci in Four Academic Medical Centers

Overview of attention for article published in Infection control and hospital epidemiology (Online), January 2015
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Title
Effect of the Increasing Use of Piperacillin/Tazobactam on the Incidence of Vancomycin-Resistant Enterococci in Four Academic Medical Centers
Published in
Infection control and hospital epidemiology (Online), January 2015
DOI 10.1086/502409
Pubmed ID
Authors

Usha Stiefel, David L. Paterson, Nicole J. Pultz, Steven M. Gordon, David C. Aron, Curtis J. Donskey

Abstract

The substitution of piperacillin/tazobactam, ampicillin/sulbactam, or both for third-generation cephalosporins has been associated with reduced vancomycin-resistant enterococci (VRE). However, piperacillin/tazobactam came into widespread use during a period in which the prevalence of VRE increased. We hypothesized that the increasing use of piperacillin/tazobactam and other agents with relatively enhanced anti-enterococcal activity (ie, piperacillin, ampicillin/sulbactam, and ampicillin) has been associated with increased or unchanged rates of VRE in some hospitals.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 3 17%
Other 2 11%
Professor 2 11%
Researcher 2 11%
Student > Master 2 11%
Other 3 17%
Unknown 4 22%
Readers by discipline Count As %
Medicine and Dentistry 9 50%
Environmental Science 1 6%
Computer Science 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Immunology and Microbiology 1 6%
Other 1 6%
Unknown 4 22%