| Title |
Transanal total mesorectal excision: pathological results of 186 patients with mid and low rectal cancer
|
|---|---|
| Published in |
Surgical Endoscopy, November 2017
|
| DOI | 10.1007/s00464-017-5944-8 |
| Pubmed ID | |
| Authors |
F. Borja de Lacy, Jacqueline J. E. M. van Laarhoven, Romina Pena, María Clara Arroyave, Raquel Bravo, Miriam Cuatrecasas, Antonio M. Lacy |
| Abstract |
Transanal total mesorectal excision (TaTME) seems to be a valid alternative to the open or laparoscopic TME. Quality of the TME specimen is the most important prognostic factor in rectal cancer. This study shows the pathological results of the largest single-institution series published on TaTME in patients with mid and low rectal cancer. We conducted a retrospective cohort study of all consecutive patients with rectal cancer, treated by TaTME between November 2011 and June 2016. Patient data were prospectively included in a standardized database. Patients with all TNM stages of mid (5-10 cm from the anal verge) and low (0-5 cm from the anal verge) rectal cancer were included. A total of 186 patients were included. Tumor was in the mid and low rectum in, respectively, 62.9 and 37.1%. Neoadjuvant chemoradiotherapy was given in 62.4%, only radiotherapy in 3.2%, and only chemotherapy in 2.2%. Preoperative staging showed T1 in 3.2%, T2 in 20.4%, T3 in 67.7%, and T4 in 7.5%. Mesorectal resection quality was complete in 95.7% (n = 178), almost complete in 1.6% (n = 3), and incomplete in 1.1% (n = 2). Overall positive CRM (≤ 1 mm) and DRM (≤ 1 mm) were 8.1% (n = 15) and 3.2% (n = 6), respectively. The composite of complete mesorectal excision, negative CRM, and negative DRM was achieved in 88.1% (n = 155) of the patients. The median number of lymph nodes found per specimen was 14.0 (IQR 11-18). The present study showed good rates regarding total mesorectal excision, negative circumferential, and distal resection margins. As the specimen quality is a surrogate marker for survival, TaTME can be regarded as a safe method to treat patients with rectal cancer, from an oncological point of view. |
X Demographics
The data shown below were collected from the profiles of 79 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 15 | 19% |
| United States | 11 | 14% |
| United Kingdom | 6 | 8% |
| Italy | 3 | 4% |
| Mexico | 3 | 4% |
| Canada | 3 | 4% |
| Ecuador | 2 | 3% |
| India | 2 | 3% |
| Netherlands | 1 | 1% |
| Other | 10 | 13% |
| Unknown | 23 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 38 | 48% |
| Practitioners (doctors, other healthcare professionals) | 25 | 32% |
| Scientists | 13 | 16% |
| Science communicators (journalists, bloggers, editors) | 3 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 53 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 21% |
| Student > Postgraduate | 10 | 19% |
| Student > Bachelor | 5 | 9% |
| Student > Master | 5 | 9% |
| Other | 3 | 6% |
| Other | 6 | 11% |
| Unknown | 13 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 32 | 60% |
| Nursing and Health Professions | 2 | 4% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Environmental Science | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 14 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 46. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2020.
All research outputs
#920,010
of 25,759,158 outputs
Outputs from Surgical Endoscopy
#49
of 6,954 outputs
Outputs of similar age
#19,149
of 341,792 outputs
Outputs of similar age from Surgical Endoscopy
#2
of 116 outputs
Altmetric has tracked 25,759,158 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,954 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.